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Tünetek és hatóanyagok közvetett vagy közvetlen hatása

Tünetek, és a hatóanyagok közvetett vagy közvetlen hatása

Gallmet Szív+Ér kapszula: betain, B6‑, B9‑ és B12‑vitaminok, Terminalia chebula és króm hatóanyagokkal

A sorok előtti "+" jelre kattintva láthatóvá teheti, a "-" jelre kattintva pedig eltüntetheti az adott tünethez / alkalmazási területhez tartozó cikkeket és szakértői videó beszélgetéseket.

B2 – Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data

Garlic (Allium sativum L.) is a common herb consumed worldwide as functional food and traditional remedy for the prevention of infectious diseases since ancient time. Garlic and its active organosulfur compounds (OSCs) have been reported to alleviate a number of viral infections in pre-clinical and clinical investigations. However, so far no systematic review on its antiviral effects and the underlying molecular mechanisms exists. The aim of this review is to systematically summarize pre-clinical and clinical investigations on antiviral effects of garlic and its OSCs as well as to further analyse recent findings on the mechanisms that underpin these antiviral actions….

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B3 – Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an aromatic herbaceous plant that is consumed worldwide as food and traditional remedy for various diseases. It has been reported to possess several biological properties including anticarcinogenic, antioxidant, antidiabetic, renoprotective, anti-atherosclerotic, antibacterial, antifungal, and antihypertensive activities in traditional medicines. A. sativum is rich in several sulfur-containing phytoconstituents such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids such as quercetin. Extracts and isolated compounds of A. sativum have been evaluated for various biological activities…

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B4 – Assessment report on Allium sativum L., bulbus

Description of the herbal substance(s), herbal preparation(s) or combinations thereof. The aim of this report is to assess the non-clinical and clinical data available on Allium sativum for preparing a European Union herbal monograph. This report is based on the documentation published in the literature.Herbal substance(s) The composition of Allium bulbus is complex. Garlic contains volatile oil (0.1-0.36%), the major components are sulphur compounds like alliin. It contains also proteins (amino acids, glutamyl peptides…), glucides, enzymes (alliinase, peroxidase, myronidase…) Allicin is formed from alliin by the alliinase. It is considered that 1 mg of alliin is equivalent to 0.45 mg…

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D3 – Marrubium vulgare L.: A Phytochemical and Pharmacological Overview

Marrubium vulgare is a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies, M. vulgare acts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+bacteria, fungi, herpes simplex virus, and parasites such as Toxoplasma gondii, Trichomonas vaginalis, and Plasmodium berghei-berghei was recorded. Additionally, it…

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D5 – Evaluation of In Vitro Antioxidant and In Vivo Anti-inflammatory Potential of White Horehound (Marrubium vulgare L) Leaves

The present study was designed to explore the anti-inflammatory effect and antioxidant potential of the methanolic extract of Marrubium vulgare leaves, a popular traditional medicinal herb. In vivo anti-inflammatory activity was evaluated by the paw edema assay induced by Carrageenin in rat model, while antioxidant activity was evaluated by two tests: Assay of free radical-scavenging activity on DPPH and Ferric reducing antioxidant plasma (FRAP). Total phenolic and total flavonoid contents of the crude methanol extract were also determined by Folin-Ciocalteu’s phenol reagent and by aluminium chloride method, respectively. The results showed that methanol extract had high level of polyphenols (195…

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D6 – A methanolic extract of Marrubium vulgareL. suppresses inflammatory responses in isoproterenol induced myocardial infarction in rat

Marrubium vulgare (Lamiaceae) is a medicinal herb and have been shown to have strong anti-inflammatory activities. The aim of the present study was to investigate the cardio protective effects of the methanolic extract of the plant on isoproterenol-induced acute myocardial infarction (MI). It is well known that inflammation plays a key role in the development of cardiovascular diseases. The results of our study demonstrated that a methanolic extract of Marrubium vulgare has strong protective effects against isoproterenol-induced myocardial infarction and this protection possibly is mediated through its anti-inflammatory actions. Source:http://www.rps.mui.ac.ir/index.php/jrps/article/view/977/961

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Dr. Medgyesi János: hogyan gyűrd le két nap alatt a koronavírust

Dr. Medgyesi János háziorvos, üzemorvos 2 nap alatt jelentős eredményt ért el az általa elkapott COVID fertőzés kezelésével. A pozitív eredményű koronavírus teszt után 48 óra elteltével már negatív eredményt mutatott egy újabb teszt.A kezelési útmutatója így néz ki: Puritán étkezés: sok tea, leves és fehérje bevitel. Lehetőség szerint kerüljük a gyümölcsöket, édességet és szénhidrátokat. Epesav pótlás a szervezetnek, mivel a koronavírus zsírburokkal rendelkezik és a zsírt az epe bontja. Sima izom görcsoldó bevitele, ami az epehólyag kiürülését segíti. Sok pihenés, lehetőleg alvás. @medfood_diet #gyógyulás #covid #fyp #orvos #stress #vegetatív #életmód #medfood #radiografia ♬ eredeti hang – Dr. Medgyesi János…

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E11 – Efficacy of Curcumin as Adjuvant Therapy to Induce or Maintain Remission in Ulcerative Colitis Patients: an Evidence-based Clinical Review

Treatment guidelines for ulcerative colitis (UC) not yet established. Currently, mesalazine, corticosteroids, and immunomodulators are treatment options for UC. However, they are known to have unpleaseant side effects such as nausea, vomiting, headaches, hepatitis, and male infertility. Curcumin is found in Turmeric plants (Curcuma longa L.), which possesses both anti-inflammatory and antioxidant properties. This study aimed to determine whether curcumin as adjuvant therapy can induce or maintain remission in UC patients. Structured search in three database (Cochrane, PubMed, Proquest) using “Curcumin”, “remission” and “Ulcerative Colitis” as keywords. Inclusion criteria is randomized controlled trials (RCTs), meta-analysis, or systematic review using curcumin…

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E2 – Immunomodulatory activity of curcumin

Curcumin, an active ingredient present in Curcuma longa, was analysed for the immunomodulatory activity in Balb/c mice. Curcumin administration was found to increase the total WBC count (15,290) significantly on the 12th day Group of animals treated with vehicle alone showed results similar to that of normal animal (10,130 on 12th day). Curcumin increased the circulating antibody titre (512) against SRBC. Curcumin administration increased the plague forming cells (PFC) in the spleen and the maximum number of RFC was observed on the 6th day (1,130 PFC/10® spleen cells) after immunization with SRBC. Bone marrow cellularity (16.9×10 cells/femur) and a. -esterase…

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G5 – Assessment report on Sambucus nigra L., fructus

Description of the herbal substance(s), herbal preparation(s) or combinations therefore. Herbal substance(s) The herbal substance consists of the dried, ripe berries of Sambucus nigra L. (elderberry). The wrinkled, more or less spherical dropes are dark violet-black and slightly glossy with a size around 0.5 cm. Usually, they contain three, somewhat elongated stones, each of which has a seed inside the hard endocarp. Fruit stalks are occasionally present. Elderberry belongs to the family Caprifoliaceae (Wichtl 2004). Elder berries taste sweet and sourish with a characteristic aroma (Bisset and Wichtl 2001, Wichtl 2004, Hiermann 2010). Two clinical studies have been conducted by…

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Mi motiválta az AntiBac kapszula kifejlesztését? Fertőzések mellékhatásai és szövődményei ellen véd

Rövid beszélgetés az AntiBac kapszuláról, melynek kifejlesztését az alábbiak motiválták: Jelenlegi fertőzéses időszak A GALLMET kapszula tapasztalatainak továbbfejlesztése Az emberi szervezet védekezőképességének támogatása epesavakkal és gyógynövényekkel További információk a videóban! D1 Tv – Vitalitás 2021.05.28.Béky László természetgyógyász és Dr. Várhalmi Antal Miklós termékfejlesztő

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9. hírlevél: Itt van az ősz, itt van újra… a légúti fertőzések ideje is

🦠 Amennyiben megfázáshoz hasonló tüneteket tapasztalunk magunkon vagy egy hozzátartozónkon, akkor az orvos felkeresése és tanácsainak betartása mellett az alábbiak a legfontosabbak: lázcsillapítás, köhögés csillapítás, fájdalomcsillapítás, megfelelő táplálkozás és bő folyadék fogyasztás stb. (no és persze itt nem a kalapkúrára gondolunk). A fentieken túl a C- és D-vitamin, a népi gyógyászatból és a tudományos kutatásokból ismert gyógynövények is hatásosak a különböző baktérium- és vírusfertőzések, valamint megfázások tüneteinek enyhítésében, lefolyásának gyorsításában, melyek közül a legfontosabbak megtalálhatók a AntiBac 💊 összetevői között is. 🧄 Fokhagyma: egy GALLMET-Immun (AntiBac) kapszulában több gerezd fokhagyma hatóanyaga található, amely számos légúti kórokozó (baktériumok, vírusok) szaporodását gátolja….

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A megfázás, meghűlés, nátha tüneteit az AntiBac hét összetevője egyenként és szinergikusan is enyhíti!

‘A megfázás vagy meghűlés vagy nátha, a felső légutak vírusos fertőzése, amely elsősorban az orr és a torok nyálkahártyáját támadja, de a tüdőben is megjelenhet. A meghűlésnek nincs pontos tudományos és orvosi definíciója (a hideghez viszont csak annyi köze van, hogy a kórokozók szezonálisan télen aktívabbak). Leggyakoribb kórokozója a rhinovírus, de kétszáznál is többféle vírus okozhatja és néha bakteriális fertőzés is súlyosbíthatja a tüneteket. A meghűlést gyakran összetévesztik a sokkal súlyosabb influenzával. A megfázás a leggyakoribb fertőzéstípus az emberek körében. Tünetei – a súlyosság és kiterjedés szerint – többek között a köhögés, a torokfájás, az orrfolyás valamint a láz. A…

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A1 – Antiviral properties of Elderberry

Sambucus nigra products (Sambucol) have antiviral properties against different strains of influenza virus. Sambucol Elderberry Extract and its formulations activate the healthy immune system by increasing inflammatory cytokine production. Standardized elderberry liquid extract possesses antimicrobial activity against both Gram-positive bacteria of Streptococcus pyogenes and group C and G Streptococci, and the Gram-negative bacterium Branhamella catarrhalis in liquid cultures. Sambucus Formosana Nakai stem ethanol extract displayed the strong anti-HCoV-NL63 (human coronavirus NL63) potential. Source:https://www.researchgate.net/publication/340236781_Antiviral_properties_of_Elderberry

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A3 – Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses

Black elderberries (Sambucus nigra L.) are well known as supportive agents against common cold and influenza. It is further known that bacterial super-infection during an influenza virus (IV) infection can lead to severe pneumonia. We have analyzed a standardized elderberry extract (Rubini, BerryPharma AG) for its antimicrobial and antiviral activity using the microtitre broth micro-dilution assay against three Gram-positive bacteria and one Gram-negative bacteria responsible for infections of the upper respiratory tract, as well as cell culture experiments for two different strains of influenza virus. The antimicrobial activity of the elderberry extract was determined by bacterial growth experiments in liquid…

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A9 – Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms

Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A metaanalysis of randomized, controlled clinical trials Upper respiratory symptoms are often treated with over the counter drugs, antibiotics, and antiviral medications. Due to concerns about safety and efficacy, there is a demand for an alternative solution. Black elderberry (Sambucus nigra) has been used to treat cold and flu symptoms, but there are no large-scale studies or meta-analyses. This meta-analysis quantifies the effects of elderberry supplementation and evaluates moderators including vaccination status and the underlying pathology. This analysis included a total of 180 participants and evaluates moderators such as vaccination…

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AntiBac összetevőinek élettani hatásai: epesavak, bodza, kurkuma, pemetefű, andrográfisz, fokhagyma

Szakértői beszélgetés az AntiBac kapszulák összetételéről és azok élettani hatásairól, melyek a következők: A fekete bodza támogatja az emberi szervezet védelmét biztosító immunrendszert. A fokhagyma hozzájárul a bél mikrobiológiai egyensúlyának a fenntartásához, valamint a káros baktériumok és mikroorganizmusok elleni védekezéshez. A keserű andrográfisz segíti a szervezet természetes védekező képességét, különösen a felső légutak szintjén. Az orvosi pemetefű segíti a béltraktust, hozzájárul az egészséges emésztéshez, a máj és epe normál működéséhez. A kurkuma + fekete bors segíti az immunrendszert, a tüdő és a légutak egészségét, valamint az allergiákkal szembeni védelmet, jelentős hatású antioxidáns. További információk a videóban! Forrás: D1 Tv –…

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Az emésztés és az epeműködés szerepe az immunrendszer megfelelő működésében és a fertőzések elleni védekezésben

Forrás: Zöld Újság 2021. december A gyomorban a sósav nagyon sok baktérium, vírus, gomba és mikroorganizmus semlegesítését, lebontását segíti, ami nagy segítség az immunrendszerünknek, de még sokat segíthetünk az egészségünk védelmének, ha odafigyelünk a szervezetünk megfelelő epe körforgására. Az alsóbb bélszakaszokban az epének és az epesavaknak is van egy fertőtlenítő hatása, és ha nem termelődik megfelelő mennyiségű epe, akkor ezek a fertőtlenítő funkciók sem működnek megfelelően. A jelenlegi fertőzéses időszakban nemcsak a bevitt ételek felszívódásával és a vitaminok kellő mértékben szervezetbe jutásával tudjuk az immunrendszerünket támogatni. A legtöbb nyirokképlet a bél falban és a bélrendszer környékén található, amelyeknek az a…

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B13 – The association of garlic with Helicobacter pylori infection and gastric cancer risk

Background Garlic may be protective against Helicobacter pylori infection and gastric cancer development. We conducted this study to quantitatively update evidence on garlic intake and gastric cancer with the inclusion of most recent cohort studies and qualitatively summarize epidemiological studies of garlic consumption and Helicobacter pylori infection. Materials and methods PubMed, Embase, MEDLINE, and Cochrane Library were searched on April 2018. We conducted a meta-analysis to determine whether garlic intake reduced gastric cancer risk using random-effect models and a systematic review to summarize evidence on the association between garlic consumption and Helicobacter pylori infection. Risk of bias was assessed using…

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B15 – Review: antimicrobial properties of allicin used alone or in combination with other medications

Garlic (Allium sativum L.) is a well-known spice widely utilised for its medicinal properties. There is an extensive record of the many beneficial health effects of garlic which can be traced back to as early as the ancient Egyptian era. One of the most studied properties of garlic is its ability to cure certain ailments caused by infections. In the 1940s, the antimicrobial activities exhibited by garlic were first reported to be due to allicin, a volatile compound extracted from raw garlic. Since then, allicin has been widely investigated for its putative inhibitory activities against a wide range of microorganisms….

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B17 – Plants of the genus Allium as antibacterial agents: From tradition to pharmacy

Plants belonging to the genus Allium are widely cultivated and used all over the world as food and medicinal plants. Since ancient times, these plants, particularly garlic (Allium sativum L.) and onion (Allium cepa L.), have represented important components of typical recipes and traditional healing systems. Not the least of which, their use as food biopreservatives is well documented, due to the relevant antibacterial activity of their extracts and essential oils. In addition to garlic and onion, this review article deals with the main members of the genus Allium, including A. ampeloprasum (Leek), A. schoenoprasum (Chive) and A. ascalonicum (Shallot),…

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B2 – Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data

Garlic (Allium sativum L.) is a common herb consumed worldwide as functional food and traditional remedy for the prevention of infectious diseases since ancient time. Garlic and its active organosulfur compounds (OSCs) have been reported to alleviate a number of viral infections in pre-clinical and clinical investigations. However, so far no systematic review on its antiviral effects and the underlying molecular mechanisms exists. The aim of this review is to systematically summarize pre-clinical and clinical investigations on antiviral effects of garlic and its OSCs as well as to further analyse recent findings on the mechanisms that underpin these antiviral actions….

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B3 – Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an aromatic herbaceous plant that is consumed worldwide as food and traditional remedy for various diseases. It has been reported to possess several biological properties including anticarcinogenic, antioxidant, antidiabetic, renoprotective, anti-atherosclerotic, antibacterial, antifungal, and antihypertensive activities in traditional medicines. A. sativum is rich in several sulfur-containing phytoconstituents such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids such as quercetin. Extracts and isolated compounds of A. sativum have been evaluated for various biological activities…

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B8 – Garlic intake and the risk of colorectal cancer A meta-analysis

Garlic intake and the risk of colorectal cancer A meta-analysis This was a meta-analysis of epidemiological articles that aimed to estimate the association of garlic intake with the risk of colorectal cancer (CRC). Electronic databases, including the Cochrane Database of Systematic Reviews, PubMed, and EMBASE, were systemically searched from inception to May 2019 to identify related articles. In addition, a random model was used to pool the included evidence based on heterogeneity. Additionally, subgroup analyses were carried out to examine the differences between different groups. The stability of our findings was tested through sensitivity analyses. Publication bias was also assessed…

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D2 – Phytochemical screening and antiviral activity of Marrubium vulgare

Introduction Aims: The present study is to investigate the phytochemical content, cytotoxicity and antiviral activity of the crude and fractions from Marrubium vulgare. Methodology and results: The crude methanol extract and fractions using hexane, chloroform, ethyl acetate and n-butanol of M. vulgare whole plant were produced in this study. Qualitative phytochemical analysis revealed the presence of flavones aglycones and steroid in all preparations except for the hexane fraction. Carbohydrates, saponins were found present in the crude and ethyl acetate extracts while tannin was detected in the crude, ethyl acetate and butanol extracts. Anthraquinones and terpenes were detected in the hexane…

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D3 – Marrubium vulgare L.: A Phytochemical and Pharmacological Overview

Marrubium vulgare is a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies, M. vulgare acts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+bacteria, fungi, herpes simplex virus, and parasites such as Toxoplasma gondii, Trichomonas vaginalis, and Plasmodium berghei-berghei was recorded. Additionally, it…

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D4 – Chemical Characterization and Antibacterial Activity of Phases Obtained from Extracts of Artemisia herba alba, Marrubium vulgare and Pinus pinaster

Chemical Characterization and Antibacterial Activity of Phases Obtained from Extracts of Artemisia herba alba, Marrubium vulgare and Pinus pinaster The objective of this study is the phytochemical characterization and antibacterial activity of Artemisia herba alba, Marrubium vulgare and Pinus pinaster. The antibacterial potential of different fractions of ethyl acetate, diethyl ether and 1 butanol extracts of the three plants were tested on four strains of bacteria: Staphylococcus aureus, Escherichia coli, Proteus vulgaris and Pseudomonas aeruginosa. The results of phytochemical screening showed a rich and varied composition of secondary metabolites: flavonoids, tannins, terpenes, sterols, coumarins and saponins which have characterized all…

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Dr. Medgyesi János: hogyan gyűrd le két nap alatt a koronavírust

Dr. Medgyesi János háziorvos, üzemorvos 2 nap alatt jelentős eredményt ért el az általa elkapott COVID fertőzés kezelésével. A pozitív eredményű koronavírus teszt után 48 óra elteltével már negatív eredményt mutatott egy újabb teszt.A kezelési útmutatója így néz ki: Puritán étkezés: sok tea, leves és fehérje bevitel. Lehetőség szerint kerüljük a gyümölcsöket, édességet és szénhidrátokat. Epesav pótlás a szervezetnek, mivel a koronavírus zsírburokkal rendelkezik és a zsírt az epe bontja. Sima izom görcsoldó bevitele, ami az epehólyag kiürülését segíti. Sok pihenés, lehetőleg alvás. @medfood_diet #gyógyulás #covid #fyp #orvos #stress #vegetatív #életmód #medfood #radiografia ♬ eredeti hang – Dr. Medgyesi János…

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Engem is megmütöttek epével, állítólag azóta hordozom a Giardia-t.

Tisztelt GALLMET! Engem is megműtöttek epével. Ennek már 20 éve. Állítólag azóta hordozom a Giardia-t. Most lett vége a kúrának és menni kell megint vissza mérésre. Az életem egy rémálom a hányinger és hasmenés miatt. Tudnának javasolni valamit? T.I. Tisztelt T.I.! Javasoljuk, hogy a webáruházban megvehető AntiBac készítményből próbáljon ki egy kúrát. Ez azt jelenti, hogy 10 napig napi 3×1 kapszulát vegyen be normál étrend mellett az étkezések kezdetekor. Amikor ezt befejezte, akkor használja tovább a GALLMET-Natural-t. Kérjük írjon az AntiBac kúra után, hogy érez-e változást, mi a tapasztalata, hátha tudunk még segíteni Önnek. GALLMED Kft.

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Epebetegségek, vírusfertőzések, szív- és érrendszeri betegségek enyhítése étrend-kiegészítőkkel

Dr. Várhalmi Antal Miklós 30 éve foglalkozik epesavakkal és az epe körforgással. Személyes érintettség okán és azzal a céllal, hogy más embereken is segítsen kb. 10 éve létrehozott egy természetes epesav tartalmú termékcsaládot. A GALLMET epesav kapszulák már sok-sok ember emésztési, és egyéb problémáin segítettek. Az epetermelés anomáliái, az epehiányos állapotok ugyanis gyakorlatilag az egész emésztésünkre és az egészségünkre is kihatnak. További információk: https://gallmet.hu/osszes-egeszsegugyi-javaslat/emesztes-es-epe-mukodes/ Ezután mivel az epesavak az immunrendszerre is jótékony hatással vannak, kifejlesztette az AntiBac készítményt. Ebben az epesavak mellett gyógynövények (bodza, fokhagyma, kurkuma, andrográfisz, fekete bors) találhatók, melyek segítenek a különböző fertőzések tüneteinek és mellékhatásainak enyhítésében. További…

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Epesavak szerepe a szervezet fiziko-kémiai védelmében – AntiBac kapszula

Szakértői beszélgetés az AntiBac kapszuláról, melynek kifejlesztéséhez az alábbi magyar szakirodalmak is nagy segítséget nyújtottak: Dr. Bertók Lóránd professzor kutatása: az epesavak detergens (zsírbontó) hatásán alapuló fiziko-kémiai védelem Dr. Hegyi Péter: Az epesav terápia új irányai További információk a videóban! Megjelenés helye: D1 Tv – Vitalitás 2021.05.28.Béky László természetgyógyász és Dr. Várhalmi Antal Miklós fejlesztő

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Fertőzések tüneteinek enyhítése gyógynövényekkel és epesavakkal: AntiBac kapszula

Rövid beszélgetés az AntiBac kapszuláról, amely a GALLMET epesav kapszulák továbbfejlesztéséből jött létre. Az epesavak a magyar és nemzetközi tudományos kutatások alapján a káros baktériumok és lipid borítású makrovírusok ellen védelmet nyújtanak. A további összetevők: A fekete bodza támogatja az emberi szervezet védelmét biztosító immunrendszert. A fokhagyma hozzájárul a bél mikrobiológiai egyensúlyának a fenntartásához, valamint a káros baktériumok és mikroorganizmusok elleni védekezéshez. A keserű andrográfisz segíti a szervezet természetes védekező képességét, különösen a felső légutak szintjén. Az orvosi pemetefű segíti a béltraktust, hozzájárul az egészséges emésztéshez, a máj és epe normál működéséhez. A kurkuma + fekete bors segíti az immunrendszert,…

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G10 – Gram-negative versus Gram-positive bacteremia: what is more alarmin(g)?

Gram-negative bacteremia has been associated with severe sepsis, although the exact mechanism and pathophysiological diff erences among bacterial species are not well understood. In the previous issue of Critical Care, Abe and colleagues report results of a retrospective study that show a signifi cantly higher incidence of Gram-negative bacteremia among adult intensive care unit patients with septic shock than in those with sepsis or severe sepsis. In this study, C-reactive protein and IL-6 levels were signifi cantly higher in Gram-negative bacteremia than in Grampositive bacteremia. These observations suggest a distinct immunopathophysiologic behavior of sepsis in patients with Gram-negative bacteremia that…

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G16 – Az endotoxin élettani hatásai

Az endotoxin fiziológiai szerepe emberi szervezet esetében sokrétű és dózisfüggő. Ma már tudjuk, hogy az endotoxinok csak akkor fejtik ki hatásukat, ha elszabadulnak a Gram-negatív baktérium felszínéről. Ez akkor történhet meg, ha a baktérium elpusztul, vagy ha szaporodni kezd. Normális esetben az emlősök szervezetében több millió Gram-negatív baktérium él, és nem okoz egészségkárosító problémát. Kóros esetben, nagyobb mennyiségben a vérbe kerülő endotoxin hatására kialakul az endotoxémia, amely traumát és sokkot okozhat. Az endotoxinok főként a makrofágokon keresztül fejtik ki hatásukat. Ezek a védelmező szerepet játszó sejtek rendes esetben bekebelezik és lebontják a szervezetre káros anyagokat. Az élő vagy elpusztult baktériumok…

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G17 – Gram negative sepsis and shock

In the modern hospital gram negative bacteremia and the associated condition of septic shock are common occurrences. In the United States the estimated incidence of gram negative bacteremia ranges from 71,000 to 330,000 cases annually. Fatalities attributed to this disease are between 18,000 and 132,000 each year. Sepsis is defined as a systemic disease caused by microorganisms or their products in the blood. Bacteremia is the presence of viable organisms in the circulation. Gram negative bacteremia in the critically ill patient is synonymous with gram negative sepsis. Septic shock is a clinical syndrome characterized by circulatory insufficiency and inadequate tissue…

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G18 – Multirezisztens kórokozók gyakoriságának változása és ennek vonatkozásai az intenzív osztályon

Incidence of nosocomial infections and antibiotics resistance in intensive care units is increasing worldwide. Blood-stream infections of Gram-negative non-fermentive bacteria are associated with higher mortality. The aim of this study was to compare the antibiotic sensitivity of nosocomial blood-stream infections between years 2008-2010. There was no difference in the sensitivity of methycillin-resistant Staphylococcus aureus and extended-spectrum beta lactamase producing Klebsiella spp. and Escherichia coli infections between the two years examined. Antibiotic resistance of Acinetobacter baumannii and Pseudomonas infections showed a marked increase in 2010 when compared to that found in 2008: there was no multiresistant Acinetobacter infection in samples obtained…

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G9 – Gram-Negative Sepsis: a Dilemma of Modern Medicine

Gram-negative sepsis, a relatively rare clinical diagnosis only a few decades ago, is perhaps the most important infectious disease problem in hospitals today. Despite recent advances in our understanding of the pathophysiological mechanisms of sepsis and improved antimicrobial therapy, the mortality rate from gram-negative sepsis remains frustratingly high, particularly after the onset of shock. Unfortunately, many of the therapeutic methods proposed over the years for the management of sepsis and its complications have either failed to meet their initial expectations or remain unproved, despite many anecdotal reports. Recently, however, the development of new monoclonal antibodybased treatments, together with earlier recognition…

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Hogyan működik az AntiBac? Melyik baktériumok ellen hatásos?

Rövid beszélgetés az AntiBac kapszuláról, melynek működéséről az alábbiakat érdemes tudni: Az összetevők úgy lettek kiválogatva nemzetközi tudományos kutatások alapján, hogy bizonyos káros baktériumok ellen védjenek. A szervezet teljes védekezőrendszerére hatással vannak az összetevők hatóanyagai. Egyéni hatásuk mellett a különböző fertőzések szövődményeire is jó hatásúak, pl. láz, köhögés, végtagfájdalom stb. További információk a videóban! D1 Tv – Vitalitás 2021.05.28.Béky László természetgyógyász és Dr. Várhalmi Antal Miklós termékfejlesztő

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Hogyan segíthetnek az epesavak és a gyógynövények bakteriális és vírus fertőzések esetén?

Naturportal podcast 2022.08.31. Dr. Várhalmi Miklós epesavakkal és az enterohepatikus körfolyamatok kutatásával foglalkozik 30 éve.Epesavakkal kapcsolatos termékek fejlesztője. Mik az epesavak? Miben tudnak segíteni? Hogyan hatnak az epesavak az immunrendszerre? Hogyan segíthetnek az epesavak a vírusok és a baktériumok esetén? Miben segíthet az orvosi pemetefű, a fekete bodza, a fokhagyma, az andrográfisz, a kurkuma, a fekete bors és a komplexen? Milyen gyógynövény az andrográfisz? Segíthet-e ez a komplex szer a covid és más vírusok esetén? Milyen bakteriális fertőzésekben segíthet? A műsorvezetők: dr. Jung Andrea Naturportal Online Magazin: https://naturportal.hu/ Természetgyógyászok, pszichológusok, coach-ok, testi-lelki Segítők keresője: https://gyogyaszkereso.hu/ Császi András természetgyógyász, egészségfejlesztő https://vitalitasbolt.hu/

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Mi motiválta az AntiBac kapszula kifejlesztését? Fertőzések mellékhatásai és szövődményei ellen véd

Rövid beszélgetés az AntiBac kapszuláról, melynek kifejlesztését az alábbiak motiválták: Jelenlegi fertőzéses időszak A GALLMET kapszula tapasztalatainak továbbfejlesztése Az emberi szervezet védekezőképességének támogatása epesavakkal és gyógynövényekkel További információk a videóban! D1 Tv – Vitalitás 2021.05.28.Béky László természetgyógyász és Dr. Várhalmi Antal Miklós termékfejlesztő

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Miben más a Gallmet Immune (AntiBac) mint a Natural és Mix? Átfogó hatás az immunrendszer támogatására

Beszélgetés az AntiBac kapszuláról, melyből kiderül, hogy miben más az AntiBac, mint a GALLMET: Az AntiBac összetevői szinergikusan hatnak az emberi szervezetre, míg a GALLMET főként az emésztőrendszerre További információk a videóban! Forrás: D1 Tv – Vitalitás 2021.05.28.Béky László természetgyógyász és Dr. Várhalmi Antal Miklós termékfejlesztő

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Mit tehetünk különböző fertőzések tüneteinek enyhítésére és gyorsabb lefolyása érdekében?

A fertőzés kórokozók káros megtelepedését jelenti egy gazdaszervezetben. A fertőzéskor a fertőző organizmus a gazdaszervezet erőforrásait kívánja felhasználni annak érdekében, hogy szaporodjon. A fertőző élőlény a normálistól eltérő funkciót is okozhat, esetleg el is pusztíthatja a gazdaszervezetet. A baktérium és vírus fertőzések legjellemzőbb tünetei az alábbiak: láz, végtag- és ízületi fájdalom, orrfolyás, orrdugulás, torokfájás köhögés, tüsszögés fejfájás, gyengeség, levertség, hidegrázás, emésztési problémák (székrekedés vagy hasmenés), kiütések és egyéb bőrproblémák stb. Az orvos felkeresése és tanácsainak betartása mellett az alábbiak a legfontosabbak: lázcsillapítás, köhögés csillapítás, orrdugulás csökkentés, fájdalomcsillapítás, bő folyadék fogyasztás, megfelelő táplálkozás, vitamin – ásványi só – nyomelem pótlás stb….

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Epesavak közvetlen, vagy közvetett hatása: Emésztés támogatása – zsírok lebontása – Puffadás enyhítése

Emésztés támogatása – zsírok lebontása epesav segítségével

Epesavak hatása

Epesavak közvetlen, vagy közvetett hatása: Epehólyag műtét esetén támogatás

C12 – A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection

A randomized, double blind placebo controlled clinical study was conducted to evaluate the efficacy of KalmCold™, an extract of Andrographis paniculata, in patients with uncomplicated upper respiratory tract infection (URTI). The assessment involved quantification of symptom scores by Visual Analogue Scale. Nine self evaluated symptoms of cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance were scored. A total of 223 patients of both sexes were randomized in two groups which received either KalmCold™ (200 mg/day) or placebo in a double blind manner. In both the treatments, mean scores of all symptoms showed a decreasing trend…

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Epesavak közvetlen, vagy közvetett hatása: Hozzájárul a gombás fertőzések hatásának enyhítéséhez, szerepet játszik a jó bélbaktériumok mennyiségének szinten tartásában

E15 – Vasodilating, spasmolytic, inotropic and chronotropic activities of curcuminoids from Curcuma longa in isolated organ preparations of guinea pigs

Turmeric is a yellowish orange spice, widely used in Asian cuisine and obtained from the rhizome of Curcuma longa. It is a mixture of three curcuminoids namely, curcumin, demethoxycurcumin and bisdemethoxycurcumin. Turmeric has been used as a medicinal substance since ancient times for respiratory and gastrointestinal problems. The aim of the present study was to investigate which curcuminoid contributes to the observed pharmacological activities, all three curcuminoids, the major curcumin metabolite tetrahydrocurcumin, and the non-enzymatic curcumin hydrolysis products ferulic acid, feruloyl methane and vanillin were analyzed for spasmolytic, inotropic and chronotropic activity. Furthermore, their uptake in respective tissue samples was…

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A1 – Antiviral properties of Elderberry

Sambucus nigra products (Sambucol) have antiviral properties against different strains of influenza virus. Sambucol Elderberry Extract and its formulations activate the healthy immune system by increasing inflammatory cytokine production. Standardized elderberry liquid extract possesses antimicrobial activity against both Gram-positive bacteria of Streptococcus pyogenes and group C and G Streptococci, and the Gram-negative bacterium Branhamella catarrhalis in liquid cultures. Sambucus Formosana Nakai stem ethanol extract displayed the strong anti-HCoV-NL63 (human coronavirus NL63) potential. Source:https://www.researchgate.net/publication/340236781_Antiviral_properties_of_Elderberry

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A3 – Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses

Black elderberries (Sambucus nigra L.) are well known as supportive agents against common cold and influenza. It is further known that bacterial super-infection during an influenza virus (IV) infection can lead to severe pneumonia. We have analyzed a standardized elderberry extract (Rubini, BerryPharma AG) for its antimicrobial and antiviral activity using the microtitre broth micro-dilution assay against three Gram-positive bacteria and one Gram-negative bacteria responsible for infections of the upper respiratory tract, as well as cell culture experiments for two different strains of influenza virus. The antimicrobial activity of the elderberry extract was determined by bacterial growth experiments in liquid…

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G10 – Gram-negative versus Gram-positive bacteremia: what is more alarmin(g)?

Gram-negative bacteremia has been associated with severe sepsis, although the exact mechanism and pathophysiological diff erences among bacterial species are not well understood. In the previous issue of Critical Care, Abe and colleagues report results of a retrospective study that show a signifi cantly higher incidence of Gram-negative bacteremia among adult intensive care unit patients with septic shock than in those with sepsis or severe sepsis. In this study, C-reactive protein and IL-6 levels were signifi cantly higher in Gram-negative bacteremia than in Grampositive bacteremia. These observations suggest a distinct immunopathophysiologic behavior of sepsis in patients with Gram-negative bacteremia that…

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G17 – Gram negative sepsis and shock

In the modern hospital gram negative bacteremia and the associated condition of septic shock are common occurrences. In the United States the estimated incidence of gram negative bacteremia ranges from 71,000 to 330,000 cases annually. Fatalities attributed to this disease are between 18,000 and 132,000 each year. Sepsis is defined as a systemic disease caused by microorganisms or their products in the blood. Bacteremia is the presence of viable organisms in the circulation. Gram negative bacteremia in the critically ill patient is synonymous with gram negative sepsis. Septic shock is a clinical syndrome characterized by circulatory insufficiency and inadequate tissue…

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G18 – Multirezisztens kórokozók gyakoriságának változása és ennek vonatkozásai az intenzív osztályon

Incidence of nosocomial infections and antibiotics resistance in intensive care units is increasing worldwide. Blood-stream infections of Gram-negative non-fermentive bacteria are associated with higher mortality. The aim of this study was to compare the antibiotic sensitivity of nosocomial blood-stream infections between years 2008-2010. There was no difference in the sensitivity of methycillin-resistant Staphylococcus aureus and extended-spectrum beta lactamase producing Klebsiella spp. and Escherichia coli infections between the two years examined. Antibiotic resistance of Acinetobacter baumannii and Pseudomonas infections showed a marked increase in 2010 when compared to that found in 2008: there was no multiresistant Acinetobacter infection in samples obtained…

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G9 – Gram-Negative Sepsis: a Dilemma of Modern Medicine

Gram-negative sepsis, a relatively rare clinical diagnosis only a few decades ago, is perhaps the most important infectious disease problem in hospitals today. Despite recent advances in our understanding of the pathophysiological mechanisms of sepsis and improved antimicrobial therapy, the mortality rate from gram-negative sepsis remains frustratingly high, particularly after the onset of shock. Unfortunately, many of the therapeutic methods proposed over the years for the management of sepsis and its complications have either failed to meet their initial expectations or remain unproved, despite many anecdotal reports. Recently, however, the development of new monoclonal antibodybased treatments, together with earlier recognition…

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Epesavak közvetlen, vagy közvetett hatása: Támogatja az immunrendszert, hozzájárul a természetes ellenálló képességhez, a fiziko-kémiai védelemhez / baktérium és vírusölő hatáshoz

B2 – Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data

Garlic (Allium sativum L.) is a common herb consumed worldwide as functional food and traditional remedy for the prevention of infectious diseases since ancient time. Garlic and its active organosulfur compounds (OSCs) have been reported to alleviate a number of viral infections in pre-clinical and clinical investigations. However, so far no systematic review on its antiviral effects and the underlying molecular mechanisms exists. The aim of this review is to systematically summarize pre-clinical and clinical investigations on antiviral effects of garlic and its OSCs as well as to further analyse recent findings on the mechanisms that underpin these antiviral actions….

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B3 – Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an aromatic herbaceous plant that is consumed worldwide as food and traditional remedy for various diseases. It has been reported to possess several biological properties including anticarcinogenic, antioxidant, antidiabetic, renoprotective, anti-atherosclerotic, antibacterial, antifungal, and antihypertensive activities in traditional medicines. A. sativum is rich in several sulfur-containing phytoconstituents such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids such as quercetin. Extracts and isolated compounds of A. sativum have been evaluated for various biological activities…

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C1. Andrographis paniculata Extract (HMPL-004) for Active Ulcerative Colitis

Andrographis paniculata has in vitro inhibitory activity against TNF-a, IL-1p and NF-KB. A pilot study of A. paniculata extract (HMPL-004) suggested similar ef.cacy to mesalamine for ulcerative colitis. A randomized, double-blind, placebo-controlled trial evaluated the ef.cacy of A. paniculata extract (HMPL-004) in 224 adults with mild-to-moderate ulcerative colitis. Patients were randomized to A. paniculata extract (HMPL-004) 1,200 mg or 1,800 mg daily or placebo for 8 weeks. In total, 45 and 60 % of patients receiving A. paniculata 1,200 mg and 1,800 mg daily, respectively, were in clinical response at week 8, compared with 40 % of those who received…

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C16 – Review on liver inflammation and antiinflammatory activity of Andrographis paniculata for hepatoprotection

Till to date, the advancement of medical science and technology is still unable to provide inclusive treatment to liver inflammation caused by neither microbial invasion nor antibiotics nor environmental toxins. Therefore, this article provides the basic knowledge of liver inflammation up to the cellular level and its current medical treatment for inflammatory symptom suppression. Because of the adverse effects of drug treatment, people start looking for comprehensive alternative nowadays. Herbal medicine is believed to be the best of choice because it is being practiced until now for centuries. Although numerous herbal plants have been reported for their efficacies in liver…

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C6 – Broad-spectrum antiviral properties of andrographolide

Broad-spectrum antiviral properties of andrographolide Andrographolide, a diterpenoid, is known for its anti-inflammatory effects. It can be isolated from various plants of the genus Andrographis, commonly known as ‘creat’. This purified compound has been tested for its anti-inflammatory effects in various stressful conditions, such as ischemia, pyrogenesis, arthritis, hepatic or neural toxicity, carcinoma, and oxidative stress, Apart from its anti-inflammatory effects, andrographolide also exhibits immunomodulatory effects by effectively enhancing cytotoxic T cells, natural killer (NK) cells, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC). All these properties of andrographolide form the foundation for the use of this miraculous compound to restrain virus…

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C7 – Fah Talai Jone proven effective in improving condition of COVID- 19 patients – DTAM

Extracts from the Fah Talai Jone (Andrographis Paniculata) medicinal plant have proven effective in improving the condition of those infected with COVID-19, after the traditional medicine was administered during clinical trials, jointly conducted by the Faculty of Medicine of Siriraj hospital, the Chulabhorn Research Institute, the Medical Science Department, the Government Pharmaceutical Organization and the Department of Thai Traditional and Alternative Medicine (DTAM). Source: https://www.thaipbsworld.com/fah-talai-jone-proven-effective-in-improving-condition-of-covid-19-patients-dtam/

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C8 – Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond

Andrographis paniculata Wall (family Acanthaceae) is one of the most popular medicinal plants used traditionally for the treatment of array of diseases such as cancer, diabetes, high blood pressure, ulcer, leprosy, bronchitis, skin diseases, flatulence, colic, influenza, dysentery, dyspepsia and malaria for centuries in Asia, America and Africa continents. It possesses several photochemical constituents with unique and interesting biological properties. This review describes the past and present state of research on Andrographis paniculata with respect to the medicinal usage, phytochemistry, pharmacological activities, toxicity profile and therapeutic usage, in order to bridge the gap requiring future research opportunities. This review is…

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C9 – Randomised clinical trial: herbal extract HMPL-004 in active ulcerative colitis – a double-blind comparison with sustained release mesalazine

Andrographis paniculatais an herbal mixture used to treat inflammatory diseases.An extract of the herb, HMPL-004, inhibits TNF-aand IL-1b,andprevents colitis in animal models. To determine the efficacy and safety of HMPL-004 in patients with mildto-moderate ulcerative colitis. A randomised, double-blind, multicentre, 8-week parallel group study was conducted using HMPL-004 1200 mg ⁄ day compared with 4500 mg ⁄ day of slow release mesalazine (mesalamine) granules in patients with mild-tomoderately active ulcerative colitis. Disease activity was assessed at baseline and every 2 weeks for clinical response, and at baseline and 8 weeks by colonoscopy. One hundred and twenty patients at five centres…

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D3 – Marrubium vulgare L.: A Phytochemical and Pharmacological Overview

Marrubium vulgare is a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies, M. vulgare acts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+bacteria, fungi, herpes simplex virus, and parasites such as Toxoplasma gondii, Trichomonas vaginalis, and Plasmodium berghei-berghei was recorded. Additionally, it…

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D5 – Evaluation of In Vitro Antioxidant and In Vivo Anti-inflammatory Potential of White Horehound (Marrubium vulgare L) Leaves

The present study was designed to explore the anti-inflammatory effect and antioxidant potential of the methanolic extract of Marrubium vulgare leaves, a popular traditional medicinal herb. In vivo anti-inflammatory activity was evaluated by the paw edema assay induced by Carrageenin in rat model, while antioxidant activity was evaluated by two tests: Assay of free radical-scavenging activity on DPPH and Ferric reducing antioxidant plasma (FRAP). Total phenolic and total flavonoid contents of the crude methanol extract were also determined by Folin-Ciocalteu’s phenol reagent and by aluminium chloride method, respectively. The results showed that methanol extract had high level of polyphenols (195…

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D6 – A methanolic extract of Marrubium vulgareL. suppresses inflammatory responses in isoproterenol induced myocardial infarction in rat

Marrubium vulgare (Lamiaceae) is a medicinal herb and have been shown to have strong anti-inflammatory activities. The aim of the present study was to investigate the cardio protective effects of the methanolic extract of the plant on isoproterenol-induced acute myocardial infarction (MI). It is well known that inflammation plays a key role in the development of cardiovascular diseases. The results of our study demonstrated that a methanolic extract of Marrubium vulgare has strong protective effects against isoproterenol-induced myocardial infarction and this protection possibly is mediated through its anti-inflammatory actions. Source:http://www.rps.mui.ac.ir/index.php/jrps/article/view/977/961

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E1 – Curcuma longa L. ameliorates asthma control in children and adolescents: A randomized, double-blind, controlled trial

Roots of Curcuma longa L. are used as medicine for millennia. They possess several pharmacological properties, including anti-inflammatory action, and can be suitable for asthma treatment. We aimed to test the hypothesis that, in children and adolescents with persistent asthma, the administration of powdered roots of C. longa for 6 months, in addition to standard treatment, compared to placebo, will result in better disease control. Patients and methods: We conducted a randomized, double-blind, placebo-controlled, phase II clinical trial. Patients were randomly assigned to receive 30 mg/kg/day of C. longa for 6 months, or placebo. Data were collected prospectively. All patients…

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E11 – Efficacy of Curcumin as Adjuvant Therapy to Induce or Maintain Remission in Ulcerative Colitis Patients: an Evidence-based Clinical Review

Treatment guidelines for ulcerative colitis (UC) not yet established. Currently, mesalazine, corticosteroids, and immunomodulators are treatment options for UC. However, they are known to have unpleaseant side effects such as nausea, vomiting, headaches, hepatitis, and male infertility. Curcumin is found in Turmeric plants (Curcuma longa L.), which possesses both anti-inflammatory and antioxidant properties. This study aimed to determine whether curcumin as adjuvant therapy can induce or maintain remission in UC patients. Structured search in three database (Cochrane, PubMed, Proquest) using “Curcumin”, “remission” and “Ulcerative Colitis” as keywords. Inclusion criteria is randomized controlled trials (RCTs), meta-analysis, or systematic review using curcumin…

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E12 – Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials Although turmeric and its curcumin-enriched extracts have been used for treating arthritis, no systematic review and meta-analysis of randomized clinical trials (RCTs) have been conducted to evaluate the strength of the research. We systemically evaluated all RCTs of turmeric extracts and curcumin for treating arthritis symptoms to elucidate the efficacy of curcuma for alleviating the symptoms of arthritis. Literature searches were conducted using 12 electronic databases, including PubMed, Embase, Cochrane Library, Korean databases, Chinese medical databases, and Indian…

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E19 – Oral bioavailability of curcumin: problems and advancements

Curcumin is a natural compound of Curcuma longa L. and has shown many pharmacological activities such as anti‐inflammatory, anti‐oxidant in both preclinical and clinical studies. Moreover, curcumin has hepatoprotective, neuroprotective activities and protects against myocardial infarction. Particularly, curcumin has also demonstrated favorite anticancer efficacy. But limiting factors such as its extremely low oral bioavailability hampers its application as therapeutic agent. Therefore, many technologies have been developed and applied to overcome this limitation. This review described the main physicochemical properties of curcumin and summarized the recent studies in the design and development of oral delivery systems for curcumin to enhance the…

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E21 – Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type1/type2 helper T-cells (Th1/Th2) balance in a mouse model of food allergy

Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type1/type2 helper T-cells (Th1/Th2) balance in a mouse model of food allergy Turmeric (Curcuma longa) has traditionally been used to treat pain, fever, allergic and inflammatory diseases such as bronchitis, arthritis, and dermatitis. In particular, turmeric and its active component, curcumin, were effective in ameliorating immune disorders including allergies. However, the effects of turmeric and curcumin have not yet been tested on food allergies. Mice were immunized with intraperitoneal ovalbumin (OVA) and alum. The mice were orally challenged with 50mg OVA, and treated with turmeric extract (100mg/kg), curcumin (3mg/kg or 30…

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E4 – Curcuma longa L. ameliorates asthma control in children and adolescents

Curcuma longa L. ameliorates asthma control in children and adolescents: A randomized, double-blind, controlled trial Roots of Curcuma longa L. are used as medicine for millennia. They possess several pharmacological properties, including anti-inflammatory action, and can be suitable for asthma treatment. We aimed to test the hypothesis that, in children and adolescents with persistent asthma, the administration of powdered roots of C. longa for 6 months, in addition to standard treatment, compared to placebo, will result in better disease control. We conducted a randomized, double-blind, placebo-controlled, phase II clinical trial. Patients were randomly assigned to receive 30 mg/kg/day of C….

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E7 – Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kB inhibition

Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF‑kB inhibition Curcumin, a polyphenol compound from Curcuma longa L. has been used for centuries as an anti-inflammatory remedy including asthma. Curcumin has been reported to exert an anti-inflammatory effect, in part, through inhibition of the NF-kB pathway. The purposes of this study were to determine whether curcumin inhibits NF-kB dependent transcription in vitro, and test whether treatment with curcumin reduces allergen-induced airway inflammation and hyper-responsiveness in a mouse model of asthma through inhibition of NF-kB pathway. The effect of curcumin on NF-kB transcriptional activity was investigated using a cell-based…

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E8 – Curcumin (a constituent of turmeric): New treatment option against COVID-19

In late December 2019, the outbreak of respiratory illness emerged in Wuhan, China, and spreads worldwide. World Health Organization (WHO) named this disease severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused by a new member of beta coronaviruses. Several medications are prescribed to patients, and some clinical trials are underway. Scientists are trying to find a specific drug against this virus. In this review, we summarize the pathogenesis, clinical features, and current treatments of coronavirus disease 2019 (COVID-19). Then, we describe the possible therapeutic effects of curcumin and its molecular mechanism against coronavirus-19. Curcumin, as an active constituent of Curcuma…

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F33 – Bile Acid Metabolism and Signaling

Bile acids are important physiological agents for intestinal nutrient absorption and biliary secretion of lipids, toxic metabolites, and xenobiotics. Bile acids also are signaling molecules and metabolic regulators that activate nuclear receptors and G protein-coupled receptor (GPCR) signaling to regulate hepatic lipid, glucose, and energy homeostasis and maintain metabolic homeostasis. Conversion of cholesterol to bile acids is critical for maintaining cholesterol homeostasis and preventing accumulation of cholesterol, triglycerides, and toxic metabolites, and injury in the liver and other organs. Enterohepatic circulation of bile acids from the liver to intestine and back to the liver plays a central role in nutrient…

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Epesavak közvetlen, vagy közvetett hatása: Hasmenés – Székrekedés enyhítése

Epesavak közvetlen, vagy közvetett hatása: Részt vesz a homloküreg gyulladás, arcüreg gyulladás, garat és gége hurut enyhítésében

AntiBac összetevőinek élettani hatásai: epesavak, bodza, kurkuma, pemetefű, andrográfisz, fokhagyma

Szakértői beszélgetés az AntiBac kapszulák összetételéről és azok élettani hatásairól, melyek a következők: A fekete bodza támogatja az emberi szervezet védelmét biztosító immunrendszert. A fokhagyma hozzájárul a bél mikrobiológiai egyensúlyának a fenntartásához, valamint a káros baktériumok és mikroorganizmusok elleni védekezéshez. A keserű andrográfisz segíti a szervezet természetes védekező képességét, különösen a felső légutak szintjén. Az orvosi pemetefű segíti a béltraktust, hozzájárul az egészséges emésztéshez, a máj és epe normál működéséhez. A kurkuma + fekete bors segíti az immunrendszert, a tüdő és a légutak egészségét, valamint az allergiákkal szembeni védelmet, jelentős hatású antioxidáns. További információk a videóban! Forrás: D1 Tv –…

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B16 – Preventing the Common Cold With a Garlic Supplement

One hundred forty-six volunteers were randomized to receive a placebo or an allicin-containing garlic supplement, one capsule daily, over a 12-week period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. The active-treatment group had significantly fewer colds than the place­bo group (24 vs 65, P<.001). The placebo group, in contrast, recorded signifi­cantly more days challenged virally (366 vs 111, P<.005) and a significantly longer duration of symptoms (5.01 vs 1.52 days, P<.001). Consequently, volun­teers in the active group were less likely to get…

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B21, C10 – COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?

COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy? The outbreak of Coronavirus SARS-Cov-2 disease (COVID-19) in Wuhan (China) in late 2019 and its Worldwide spread has caused hundreds of thousands of deaths so far. As of July 2020, the disease seems to be mostly affecting Europe and the Americas. Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. Older people and those with underlying medical problems such as cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to develop serious illness…

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C12 – A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection

A randomized, double blind placebo controlled clinical study was conducted to evaluate the efficacy of KalmCold™, an extract of Andrographis paniculata, in patients with uncomplicated upper respiratory tract infection (URTI). The assessment involved quantification of symptom scores by Visual Analogue Scale. Nine self evaluated symptoms of cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance were scored. A total of 223 patients of both sexes were randomized in two groups which received either KalmCold™ (200 mg/day) or placebo in a double blind manner. In both the treatments, mean scores of all symptoms showed a decreasing trend…

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C13 – A randomized, controlled study of Kan Jang versus amantadine in the treatment of influenza in Volgograd

Two randomized, parallel-group clinical studies with a verum and a control group were performed to investigate the effect of a standardized extract (SHA-10) of Andrographis panaiculata (N.) fixed combination Kan Jang in the treatment of diagnosed influenza viral infection. The pilot study was performed on 540 patients with 71 Kan Jang-treated patients with the second phase conducted enrolling 66 patients. The differences in the duration of sick leave and frequency of post-influenza complications indicate that the Kan Jang phytopreparation not only contributes to quicker recovery, but also reduces the risk of post-influenza complications. Kan Jang was well tolerated by patients….

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C17 – Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children

Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children: A systematic review and meta-analysis Introduction: Antimicrobial resistance (AMR) is a substantial threat to public health. Safe and effective alternatives are required to reduce unnecessary antibiotic prescribing. Andrographis Paniculata (A. Paniculata, Chuān Xīn LiaÂn) has traditionally been used in Indian and Chinese herbal medicine for cough, cold and influenza, suggesting a role in respiratory tract infections (RTIs). This systematic review aimed to evaluate the clinical effectiveness and safety of A. Paniculata for symptoms of acute RTIs (ARTIs). Results: Thirty-three RCTs (7175 patients) were…

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E1 – Curcuma longa L. ameliorates asthma control in children and adolescents: A randomized, double-blind, controlled trial

Roots of Curcuma longa L. are used as medicine for millennia. They possess several pharmacological properties, including anti-inflammatory action, and can be suitable for asthma treatment. We aimed to test the hypothesis that, in children and adolescents with persistent asthma, the administration of powdered roots of C. longa for 6 months, in addition to standard treatment, compared to placebo, will result in better disease control. Patients and methods: We conducted a randomized, double-blind, placebo-controlled, phase II clinical trial. Patients were randomly assigned to receive 30 mg/kg/day of C. longa for 6 months, or placebo. Data were collected prospectively. All patients…

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E4 – Curcuma longa L. ameliorates asthma control in children and adolescents

Curcuma longa L. ameliorates asthma control in children and adolescents: A randomized, double-blind, controlled trial Roots of Curcuma longa L. are used as medicine for millennia. They possess several pharmacological properties, including anti-inflammatory action, and can be suitable for asthma treatment. We aimed to test the hypothesis that, in children and adolescents with persistent asthma, the administration of powdered roots of C. longa for 6 months, in addition to standard treatment, compared to placebo, will result in better disease control. We conducted a randomized, double-blind, placebo-controlled, phase II clinical trial. Patients were randomly assigned to receive 30 mg/kg/day of C….

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E7 – Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kB inhibition

Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF‑kB inhibition Curcumin, a polyphenol compound from Curcuma longa L. has been used for centuries as an anti-inflammatory remedy including asthma. Curcumin has been reported to exert an anti-inflammatory effect, in part, through inhibition of the NF-kB pathway. The purposes of this study were to determine whether curcumin inhibits NF-kB dependent transcription in vitro, and test whether treatment with curcumin reduces allergen-induced airway inflammation and hyper-responsiveness in a mouse model of asthma through inhibition of NF-kB pathway. The effect of curcumin on NF-kB transcriptional activity was investigated using a cell-based…

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B10 – Garlic consumption and colorectal cancer risk in man: a systematic review and meta-analysis

Colorectal cancer shows large incidence variations worldwide that have been attributed to different dietary factors. We conducted a meta-analysis on the relationship between garlic consumption and colorectal cancer risk. We systematically reviewed publications obtained by searching ISI Web of Knowledge, MEDLINE and EMBASE literature databases. We extracted the risk estimate of the highest and the lowest reported categories of intake from each study and conducted meta-analysis using a random-effects model. The pooled analysis of all fourteen studies, seven cohort and seven case– control, indicated that garlic consumption was not associated with colorectal cancer risk (OR = 0·93; 95 % CI…

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B13 – The association of garlic with Helicobacter pylori infection and gastric cancer risk

Background Garlic may be protective against Helicobacter pylori infection and gastric cancer development. We conducted this study to quantitatively update evidence on garlic intake and gastric cancer with the inclusion of most recent cohort studies and qualitatively summarize epidemiological studies of garlic consumption and Helicobacter pylori infection. Materials and methods PubMed, Embase, MEDLINE, and Cochrane Library were searched on April 2018. We conducted a meta-analysis to determine whether garlic intake reduced gastric cancer risk using random-effect models and a systematic review to summarize evidence on the association between garlic consumption and Helicobacter pylori infection. Risk of bias was assessed using…

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B16 – Preventing the Common Cold With a Garlic Supplement

One hundred forty-six volunteers were randomized to receive a placebo or an allicin-containing garlic supplement, one capsule daily, over a 12-week period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. The active-treatment group had significantly fewer colds than the place­bo group (24 vs 65, P<.001). The placebo group, in contrast, recorded signifi­cantly more days challenged virally (366 vs 111, P<.005) and a significantly longer duration of symptoms (5.01 vs 1.52 days, P<.001). Consequently, volun­teers in the active group were less likely to get…

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B19. Allicin as add-on therapy for Helicobacter pylori infection: A systematic review and meta-analysis

Allicin (2-propene-1-sulfinothioic acid S-2-propenyl ester, diallyl thiosulfinate) extracted from garlic, has proven activity against Helicobacter pylori (H. Pylori) infection. In recent years, clinical trials have explored its utility as an add-on therapy with variable outcomes reported. To perform a systemic review of allicin as an add-on treatment for H. Pylori infection and assess its efficacy in randomized controlled trials (RCTs). Electronic databases including MEDLINE, EMBASE, the Web of Science, the Cochrane Database, the China National Knowledge Infrastructure Database, Chinese VIP Information Databases, Chinese Medical Databases, and the Wan-Fang Database were searched for keywords including “allicin”, “Helicobacter pylori”, “randomized clinical trials”,…

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B2 – Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data

Garlic (Allium sativum L.) is a common herb consumed worldwide as functional food and traditional remedy for the prevention of infectious diseases since ancient time. Garlic and its active organosulfur compounds (OSCs) have been reported to alleviate a number of viral infections in pre-clinical and clinical investigations. However, so far no systematic review on its antiviral effects and the underlying molecular mechanisms exists. The aim of this review is to systematically summarize pre-clinical and clinical investigations on antiviral effects of garlic and its OSCs as well as to further analyse recent findings on the mechanisms that underpin these antiviral actions….

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C2. Andrographis paniculata (Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry, and Pharmacology

The demand of AP is greatly increased in the past few years for its overwhelming therapeutic potentials. Available data on AP also clearly expresses a broad spectrum of pharmacological properties of this plant. Due to possessing extensive pharmacological activities, the AP can be safely regarded as one of the modern catholicons. However, the investigated pharmacological activities of AP need validation through the clinical study. Though several clinical studies were successfully completed without adverse effects or fatalities, most of them only investigated upper respiratory tract infections for a variety of conditions. Verification of the efficacy of other biological activities of AP…

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C8 – Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond

Andrographis paniculata Wall (family Acanthaceae) is one of the most popular medicinal plants used traditionally for the treatment of array of diseases such as cancer, diabetes, high blood pressure, ulcer, leprosy, bronchitis, skin diseases, flatulence, colic, influenza, dysentery, dyspepsia and malaria for centuries in Asia, America and Africa continents. It possesses several photochemical constituents with unique and interesting biological properties. This review describes the past and present state of research on Andrographis paniculata with respect to the medicinal usage, phytochemistry, pharmacological activities, toxicity profile and therapeutic usage, in order to bridge the gap requiring future research opportunities. This review is…

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D2 – Phytochemical screening and antiviral activity of Marrubium vulgare

Introduction Aims: The present study is to investigate the phytochemical content, cytotoxicity and antiviral activity of the crude and fractions from Marrubium vulgare. Methodology and results: The crude methanol extract and fractions using hexane, chloroform, ethyl acetate and n-butanol of M. vulgare whole plant were produced in this study. Qualitative phytochemical analysis revealed the presence of flavones aglycones and steroid in all preparations except for the hexane fraction. Carbohydrates, saponins were found present in the crude and ethyl acetate extracts while tannin was detected in the crude, ethyl acetate and butanol extracts. Anthraquinones and terpenes were detected in the hexane…

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D3 – Marrubium vulgare L.: A Phytochemical and Pharmacological Overview

Marrubium vulgare is a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies, M. vulgare acts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+bacteria, fungi, herpes simplex virus, and parasites such as Toxoplasma gondii, Trichomonas vaginalis, and Plasmodium berghei-berghei was recorded. Additionally, it…

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D4 – Chemical Characterization and Antibacterial Activity of Phases Obtained from Extracts of Artemisia herba alba, Marrubium vulgare and Pinus pinaster

Chemical Characterization and Antibacterial Activity of Phases Obtained from Extracts of Artemisia herba alba, Marrubium vulgare and Pinus pinaster The objective of this study is the phytochemical characterization and antibacterial activity of Artemisia herba alba, Marrubium vulgare and Pinus pinaster. The antibacterial potential of different fractions of ethyl acetate, diethyl ether and 1 butanol extracts of the three plants were tested on four strains of bacteria: Staphylococcus aureus, Escherichia coli, Proteus vulgaris and Pseudomonas aeruginosa. The results of phytochemical screening showed a rich and varied composition of secondary metabolites: flavonoids, tannins, terpenes, sterols, coumarins and saponins which have characterized all…

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E21 – Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type1/type2 helper T-cells (Th1/Th2) balance in a mouse model of food allergy

Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type1/type2 helper T-cells (Th1/Th2) balance in a mouse model of food allergy Turmeric (Curcuma longa) has traditionally been used to treat pain, fever, allergic and inflammatory diseases such as bronchitis, arthritis, and dermatitis. In particular, turmeric and its active component, curcumin, were effective in ameliorating immune disorders including allergies. However, the effects of turmeric and curcumin have not yet been tested on food allergies. Mice were immunized with intraperitoneal ovalbumin (OVA) and alum. The mice were orally challenged with 50mg OVA, and treated with turmeric extract (100mg/kg), curcumin (3mg/kg or 30…

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G16 – Az endotoxin élettani hatásai

Az endotoxin fiziológiai szerepe emberi szervezet esetében sokrétű és dózisfüggő. Ma már tudjuk, hogy az endotoxinok csak akkor fejtik ki hatásukat, ha elszabadulnak a Gram-negatív baktérium felszínéről. Ez akkor történhet meg, ha a baktérium elpusztul, vagy ha szaporodni kezd. Normális esetben az emlősök szervezetében több millió Gram-negatív baktérium él, és nem okoz egészségkárosító problémát. Kóros esetben, nagyobb mennyiségben a vérbe kerülő endotoxin hatására kialakul az endotoxémia, amely traumát és sokkot okozhat. Az endotoxinok főként a makrofágokon keresztül fejtik ki hatásukat. Ezek a védelmező szerepet játszó sejtek rendes esetben bekebelezik és lebontják a szervezetre káros anyagokat. Az élő vagy elpusztult baktériumok…

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G17 – Gram negative sepsis and shock

In the modern hospital gram negative bacteremia and the associated condition of septic shock are common occurrences. In the United States the estimated incidence of gram negative bacteremia ranges from 71,000 to 330,000 cases annually. Fatalities attributed to this disease are between 18,000 and 132,000 each year. Sepsis is defined as a systemic disease caused by microorganisms or their products in the blood. Bacteremia is the presence of viable organisms in the circulation. Gram negative bacteremia in the critically ill patient is synonymous with gram negative sepsis. Septic shock is a clinical syndrome characterized by circulatory insufficiency and inadequate tissue…

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G18 – Multirezisztens kórokozók gyakoriságának változása és ennek vonatkozásai az intenzív osztályon

Incidence of nosocomial infections and antibiotics resistance in intensive care units is increasing worldwide. Blood-stream infections of Gram-negative non-fermentive bacteria are associated with higher mortality. The aim of this study was to compare the antibiotic sensitivity of nosocomial blood-stream infections between years 2008-2010. There was no difference in the sensitivity of methycillin-resistant Staphylococcus aureus and extended-spectrum beta lactamase producing Klebsiella spp. and Escherichia coli infections between the two years examined. Antibiotic resistance of Acinetobacter baumannii and Pseudomonas infections showed a marked increase in 2010 when compared to that found in 2008: there was no multiresistant Acinetobacter infection in samples obtained…

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A megfázás, meghűlés, nátha tüneteit az AntiBac hét összetevője egyenként és szinergikusan is enyhíti!

‘A megfázás vagy meghűlés vagy nátha, a felső légutak vírusos fertőzése, amely elsősorban az orr és a torok nyálkahártyáját támadja, de a tüdőben is megjelenhet. A meghűlésnek nincs pontos tudományos és orvosi definíciója (a hideghez viszont csak annyi köze van, hogy a kórokozók szezonálisan télen aktívabbak). Leggyakoribb kórokozója a rhinovírus, de kétszáznál is többféle vírus okozhatja és néha bakteriális fertőzés is súlyosbíthatja a tüneteket. A meghűlést gyakran összetévesztik a sokkal súlyosabb influenzával. A megfázás a leggyakoribb fertőzéstípus az emberek körében. Tünetei – a súlyosság és kiterjedés szerint – többek között a köhögés, a torokfájás, az orrfolyás valamint a láz. A…

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A3 – Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses

Black elderberries (Sambucus nigra L.) are well known as supportive agents against common cold and influenza. It is further known that bacterial super-infection during an influenza virus (IV) infection can lead to severe pneumonia. We have analyzed a standardized elderberry extract (Rubini, BerryPharma AG) for its antimicrobial and antiviral activity using the microtitre broth micro-dilution assay against three Gram-positive bacteria and one Gram-negative bacteria responsible for infections of the upper respiratory tract, as well as cell culture experiments for two different strains of influenza virus. The antimicrobial activity of the elderberry extract was determined by bacterial growth experiments in liquid…

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A6 – Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama

Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama A standardized elderberry extract, Sambucol® (SAM), reduced hemagglutination and inhibited replication of human influenza viruses type A/Shangdong 9/93 (H3N2), A/Beijing 32/92 (H3N2), A/Texas 36/91 (HlNl), A/Singapore 6/86 (HlNl), type B/Panama 45/90, B/Yamagata 16/88, B/Ann Arbor 1/86, and of animal strains from Northern European swine and turkeys, A/Sw/Ger 2/81, A/Tur/Ger 3/91, and A/Sw/Ger 8533/91 in Madin–Darby canine kidney cells. A placebo-controlled, double blind study was carried out on a group of individuals living in…

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AntiBac összetevőinek élettani hatásai: epesavak, bodza, kurkuma, pemetefű, andrográfisz, fokhagyma

Szakértői beszélgetés az AntiBac kapszulák összetételéről és azok élettani hatásairól, melyek a következők: A fekete bodza támogatja az emberi szervezet védelmét biztosító immunrendszert. A fokhagyma hozzájárul a bél mikrobiológiai egyensúlyának a fenntartásához, valamint a káros baktériumok és mikroorganizmusok elleni védekezéshez. A keserű andrográfisz segíti a szervezet természetes védekező képességét, különösen a felső légutak szintjén. Az orvosi pemetefű segíti a béltraktust, hozzájárul az egészséges emésztéshez, a máj és epe normál működéséhez. A kurkuma + fekete bors segíti az immunrendszert, a tüdő és a légutak egészségét, valamint az allergiákkal szembeni védelmet, jelentős hatású antioxidáns. További információk a videóban! Forrás: D1 Tv –…

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Az emésztés és az epeműködés szerepe az immunrendszer megfelelő működésében és a fertőzések elleni védekezésben

Forrás: Zöld Újság 2021. december A gyomorban a sósav nagyon sok baktérium, vírus, gomba és mikroorganizmus semlegesítését, lebontását segíti, ami nagy segítség az immunrendszerünknek, de még sokat segíthetünk az egészségünk védelmének, ha odafigyelünk a szervezetünk megfelelő epe körforgására. Az alsóbb bélszakaszokban az epének és az epesavaknak is van egy fertőtlenítő hatása, és ha nem termelődik megfelelő mennyiségű epe, akkor ezek a fertőtlenítő funkciók sem működnek megfelelően. A jelenlegi fertőzéses időszakban nemcsak a bevitt ételek felszívódásával és a vitaminok kellő mértékben szervezetbe jutásával tudjuk az immunrendszerünket támogatni. A legtöbb nyirokképlet a bél falban és a bélrendszer környékén található, amelyeknek az a…

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Mit tehetünk különböző fertőzések tüneteinek enyhítésére és gyorsabb lefolyása érdekében?

A fertőzés kórokozók káros megtelepedését jelenti egy gazdaszervezetben. A fertőzéskor a fertőző organizmus a gazdaszervezet erőforrásait kívánja felhasználni annak érdekében, hogy szaporodjon. A fertőző élőlény a normálistól eltérő funkciót is okozhat, esetleg el is pusztíthatja a gazdaszervezetet. A baktérium és vírus fertőzések legjellemzőbb tünetei az alábbiak: láz, végtag- és ízületi fájdalom, orrfolyás, orrdugulás, torokfájás köhögés, tüsszögés fejfájás, gyengeség, levertség, hidegrázás, emésztési problémák (székrekedés vagy hasmenés), kiütések és egyéb bőrproblémák stb. Az orvos felkeresése és tanácsainak betartása mellett az alábbiak a legfontosabbak: lázcsillapítás, köhögés csillapítás, orrdugulás csökkentés, fájdalomcsillapítás, bő folyadék fogyasztás, megfelelő táplálkozás, vitamin – ásványi só – nyomelem pótlás stb….

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9. hírlevél: Itt van az ősz, itt van újra… a légúti fertőzések ideje is

🦠 Amennyiben megfázáshoz hasonló tüneteket tapasztalunk magunkon vagy egy hozzátartozónkon, akkor az orvos felkeresése és tanácsainak betartása mellett az alábbiak a legfontosabbak: lázcsillapítás, köhögés csillapítás, fájdalomcsillapítás, megfelelő táplálkozás és bő folyadék fogyasztás stb. (no és persze itt nem a kalapkúrára gondolunk). A fentieken túl a C- és D-vitamin, a népi gyógyászatból és a tudományos kutatásokból ismert gyógynövények is hatásosak a különböző baktérium- és vírusfertőzések, valamint megfázások tüneteinek enyhítésében, lefolyásának gyorsításában, melyek közül a legfontosabbak megtalálhatók a AntiBac 💊 összetevői között is. 🧄 Fokhagyma: egy GALLMET-Immun (AntiBac) kapszulában több gerezd fokhagyma hatóanyaga található, amely számos légúti kórokozó (baktériumok, vírusok) szaporodását gátolja….

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A megfázás, meghűlés, nátha tüneteit az AntiBac hét összetevője egyenként és szinergikusan is enyhíti!

‘A megfázás vagy meghűlés vagy nátha, a felső légutak vírusos fertőzése, amely elsősorban az orr és a torok nyálkahártyáját támadja, de a tüdőben is megjelenhet. A meghűlésnek nincs pontos tudományos és orvosi definíciója (a hideghez viszont csak annyi köze van, hogy a kórokozók szezonálisan télen aktívabbak). Leggyakoribb kórokozója a rhinovírus, de kétszáznál is többféle vírus okozhatja és néha bakteriális fertőzés is súlyosbíthatja a tüneteket. A meghűlést gyakran összetévesztik a sokkal súlyosabb influenzával. A megfázás a leggyakoribb fertőzéstípus az emberek körében. Tünetei – a súlyosság és kiterjedés szerint – többek között a köhögés, a torokfájás, az orrfolyás valamint a láz. A…

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A1 – Antiviral properties of Elderberry

Sambucus nigra products (Sambucol) have antiviral properties against different strains of influenza virus. Sambucol Elderberry Extract and its formulations activate the healthy immune system by increasing inflammatory cytokine production. Standardized elderberry liquid extract possesses antimicrobial activity against both Gram-positive bacteria of Streptococcus pyogenes and group C and G Streptococci, and the Gram-negative bacterium Branhamella catarrhalis in liquid cultures. Sambucus Formosana Nakai stem ethanol extract displayed the strong anti-HCoV-NL63 (human coronavirus NL63) potential. Source:https://www.researchgate.net/publication/340236781_Antiviral_properties_of_Elderberry

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A3 – Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses

Black elderberries (Sambucus nigra L.) are well known as supportive agents against common cold and influenza. It is further known that bacterial super-infection during an influenza virus (IV) infection can lead to severe pneumonia. We have analyzed a standardized elderberry extract (Rubini, BerryPharma AG) for its antimicrobial and antiviral activity using the microtitre broth micro-dilution assay against three Gram-positive bacteria and one Gram-negative bacteria responsible for infections of the upper respiratory tract, as well as cell culture experiments for two different strains of influenza virus. The antimicrobial activity of the elderberry extract was determined by bacterial growth experiments in liquid…

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A4 – Randomized Study of the Efficacy and Safety of Oral Elderberry Extract in the Treatment of Influenza A and B Virus Infections

Randomized Study of the Efficacy and Safety of Oral Elderberry Extract in the Treatment of Influenza A and B Virus Infections The influenza virus is an orthomyxovirus and causes an acute respiratory tract disease. Influenza is typically characterized by abrupt onset of fever, headache, myalgia, sore throat and non-productive cough. The illness is usually self-limiting, with relief of symptoms occurring within 5 – 7 days. Nevertheless, it is an important disease due to its ease of communicability, short incubation time, rapid rate of viral mutation, related morbidity, resultant loss of productivity, and the possibility of severe complications. Influenza can be…

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A5 – Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers

Intercontinental air travel can be stressful, especially for respiratory health. Elderberries have been used traditionally, and in some observational and clinical studies, as supportive agents against the common cold and influenza. This randomized, double-blind placebo-controlled clinical trial of 312 economy class passengers travelling from Australia to an overseas destination aimed to investigate if a standardised membrane filtered elderberry (Sambucus nigra L.) extract has beneficial effects on physical, especially respiratory, and mental health. Cold episodes, cold duration and symptoms were noted in a daily diary and assessed using the Jackson score. Participants also completed three surveys containing questions regarding upper respiratory…

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A6 – Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama

Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama A standardized elderberry extract, Sambucol® (SAM), reduced hemagglutination and inhibited replication of human influenza viruses type A/Shangdong 9/93 (H3N2), A/Beijing 32/92 (H3N2), A/Texas 36/91 (HlNl), A/Singapore 6/86 (HlNl), type B/Panama 45/90, B/Yamagata 16/88, B/Ann Arbor 1/86, and of animal strains from Northern European swine and turkeys, A/Sw/Ger 2/81, A/Tur/Ger 3/91, and A/Sw/Ger 8533/91 in Madin–Darby canine kidney cells. A placebo-controlled, double blind study was carried out on a group of individuals living in…

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A7 – Sambucus nigra extracts inhibit infectious bronchitis virus at an early point during replication

Background: Infectious bronchitis virus (IBV) is a pathogenic chicken coronavirus. Currently, vaccination against IBV is only partially protective; therefore, better preventions and treatments are needed. Plants produce antimicrobial secondary compounds, which may be a source for novel anti-viral drugs. Non-cytotoxic, crude ethanol extracts of Rhodiola rosea roots, Nigella sativa seeds, and Sambucus nigra fruit were tested for anti-IBV activity, since these safe, widely used plant tissues contain polyphenol derivatives that inhibit other viruses. Results: Dose–response cytotoxicity curves on Vero cells using trypan blue staining determined the highest non-cytotoxic concentrations of each plant extract. To screen for IBV inhibition, cells and…

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A9 – Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms

Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A metaanalysis of randomized, controlled clinical trials Upper respiratory symptoms are often treated with over the counter drugs, antibiotics, and antiviral medications. Due to concerns about safety and efficacy, there is a demand for an alternative solution. Black elderberry (Sambucus nigra) has been used to treat cold and flu symptoms, but there are no large-scale studies or meta-analyses. This meta-analysis quantifies the effects of elderberry supplementation and evaluates moderators including vaccination status and the underlying pathology. This analysis included a total of 180 participants and evaluates moderators such as vaccination…

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AntiBac összetevőinek élettani hatásai: epesavak, bodza, kurkuma, pemetefű, andrográfisz, fokhagyma

Szakértői beszélgetés az AntiBac kapszulák összetételéről és azok élettani hatásairól, melyek a következők: A fekete bodza támogatja az emberi szervezet védelmét biztosító immunrendszert. A fokhagyma hozzájárul a bél mikrobiológiai egyensúlyának a fenntartásához, valamint a káros baktériumok és mikroorganizmusok elleni védekezéshez. A keserű andrográfisz segíti a szervezet természetes védekező képességét, különösen a felső légutak szintjén. Az orvosi pemetefű segíti a béltraktust, hozzájárul az egészséges emésztéshez, a máj és epe normál működéséhez. A kurkuma + fekete bors segíti az immunrendszert, a tüdő és a légutak egészségét, valamint az allergiákkal szembeni védelmet, jelentős hatású antioxidáns. További információk a videóban! Forrás: D1 Tv –…

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Az emésztés és az epeműködés szerepe az immunrendszer megfelelő működésében és a fertőzések elleni védekezésben

Forrás: Zöld Újság 2021. december A gyomorban a sósav nagyon sok baktérium, vírus, gomba és mikroorganizmus semlegesítését, lebontását segíti, ami nagy segítség az immunrendszerünknek, de még sokat segíthetünk az egészségünk védelmének, ha odafigyelünk a szervezetünk megfelelő epe körforgására. Az alsóbb bélszakaszokban az epének és az epesavaknak is van egy fertőtlenítő hatása, és ha nem termelődik megfelelő mennyiségű epe, akkor ezek a fertőtlenítő funkciók sem működnek megfelelően. A jelenlegi fertőzéses időszakban nemcsak a bevitt ételek felszívódásával és a vitaminok kellő mértékben szervezetbe jutásával tudjuk az immunrendszerünket támogatni. A legtöbb nyirokképlet a bél falban és a bélrendszer környékén található, amelyeknek az a…

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B16 – Preventing the Common Cold With a Garlic Supplement

One hundred forty-six volunteers were randomized to receive a placebo or an allicin-containing garlic supplement, one capsule daily, over a 12-week period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. The active-treatment group had significantly fewer colds than the place­bo group (24 vs 65, P<.001). The placebo group, in contrast, recorded signifi­cantly more days challenged virally (366 vs 111, P<.005) and a significantly longer duration of symptoms (5.01 vs 1.52 days, P<.001). Consequently, volun­teers in the active group were less likely to get…

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B5 – Efficacy of Garlic and Onion against virus

In the current scenario, pharmaceutical industry is dependent on chemical based drugs to treat viral infection. However, these drugs are known to induce many side effects in human body. There is pressing need to promote safe alternative to chemical based antiviral drugs. Onion and garlic are natural sources which are known to possess antiviral properties. It is well known that onion and garlic are rich source of organosulfur compounds. Organosulfur compounds like quercetin and allicin are associated with inhibition of viral infection. These chemicals can hinder virus attachment to host cell, alter transcription and translation of viral genome in host…

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B9 – Garlic Lowers Blood Pressure in Hypertensive Individuals, Regulates Serum Cholesterol, and Stimulates Immunity: An Updated Meta-analysis and Review

Garlic Lowers Blood Pressure in Hypertensive Individuals, Regulates Serum Cholesterol, and Stimulates Immunity: An Updated Meta-analysis and Review Garlic has been shown to have cardiovascular protective and immunomodulatory properties. We updated a previous meta-analysis on the effect of garlic on blood pressure and reviewed the effect of garlic on cholesterol and immunity. We searched the Medline database for randomized controlled trials (RCTs) published between 1955 and December 2013 on the effect of garlic preparations on blood pressure. In addition, we reviewed the effect of garlic on cholesterol and immunity. Our updated meta-analysis on the effect of garlic on blood pressure,…

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C12 – A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection

A randomized, double blind placebo controlled clinical study was conducted to evaluate the efficacy of KalmCold™, an extract of Andrographis paniculata, in patients with uncomplicated upper respiratory tract infection (URTI). The assessment involved quantification of symptom scores by Visual Analogue Scale. Nine self evaluated symptoms of cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance were scored. A total of 223 patients of both sexes were randomized in two groups which received either KalmCold™ (200 mg/day) or placebo in a double blind manner. In both the treatments, mean scores of all symptoms showed a decreasing trend…

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C13 – A randomized, controlled study of Kan Jang versus amantadine in the treatment of influenza in Volgograd

Two randomized, parallel-group clinical studies with a verum and a control group were performed to investigate the effect of a standardized extract (SHA-10) of Andrographis panaiculata (N.) fixed combination Kan Jang in the treatment of diagnosed influenza viral infection. The pilot study was performed on 540 patients with 71 Kan Jang-treated patients with the second phase conducted enrolling 66 patients. The differences in the duration of sick leave and frequency of post-influenza complications indicate that the Kan Jang phytopreparation not only contributes to quicker recovery, but also reduces the risk of post-influenza complications. Kan Jang was well tolerated by patients….

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C17 – Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children

Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children: A systematic review and meta-analysis Introduction: Antimicrobial resistance (AMR) is a substantial threat to public health. Safe and effective alternatives are required to reduce unnecessary antibiotic prescribing. Andrographis Paniculata (A. Paniculata, Chuān Xīn LiaÂn) has traditionally been used in Indian and Chinese herbal medicine for cough, cold and influenza, suggesting a role in respiratory tract infections (RTIs). This systematic review aimed to evaluate the clinical effectiveness and safety of A. Paniculata for symptoms of acute RTIs (ARTIs). Results: Thirty-three RCTs (7175 patients) were…

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C2. Andrographis paniculata (Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry, and Pharmacology

The demand of AP is greatly increased in the past few years for its overwhelming therapeutic potentials. Available data on AP also clearly expresses a broad spectrum of pharmacological properties of this plant. Due to possessing extensive pharmacological activities, the AP can be safely regarded as one of the modern catholicons. However, the investigated pharmacological activities of AP need validation through the clinical study. Though several clinical studies were successfully completed without adverse effects or fatalities, most of them only investigated upper respiratory tract infections for a variety of conditions. Verification of the efficacy of other biological activities of AP…

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C3 – Andrographolide and its fluorescent derivative inhibit the main proteases of 2019-nCoV and SARS-CoV through covalent linkage

Andrographolide and its fluorescent derivative inhibit the main proteases of 2019-nCoV and SARS-CoV through covalent linkage​ The coronavirus disease 2019 (COVID-19) pandemic caused by 2019 novel coronavirus (2019-nCoV) has been a crisis of global health, whereas the effective vaccines against 2019-nCoV are still under development. Alternatively, utilization of old drugs or available medicine that can suppress the viral activity or replication may provide an urgent solution to suppress the rapid spread of 2019-nCoV. Andrographolide is a highly abundant natural product of the medicinal plant, Andrographis paniculata, which has been clinically used for inflammatory diseases and anti-viral therapy. We herein demonstrate…

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C4 – Andrographolide as a potent and promising antiviral agent

Andrographolide as a potent and promising antiviral agent Andrographolide is a labdane diterpenoid extracted and purified from the aerial parts of plants belonging to genus Andrographis (Acanthaceae). The research has shown the plant based compound is low cytotoxic, having antimicrobial, anti-cancer, antiviral and anti-parasitic effects. Andrographolide both prevent spread as well as transmission of virus to neighboring cells by interfering with different cell signaling pathways. In addition to its medicinal value, plant has been found having nutritional value. Therefore being cost effective, easy availability and having nutritional value as a natural supplement, can be used to improve the quality of…

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C7 – Fah Talai Jone proven effective in improving condition of COVID- 19 patients – DTAM

Extracts from the Fah Talai Jone (Andrographis Paniculata) medicinal plant have proven effective in improving the condition of those infected with COVID-19, after the traditional medicine was administered during clinical trials, jointly conducted by the Faculty of Medicine of Siriraj hospital, the Chulabhorn Research Institute, the Medical Science Department, the Government Pharmaceutical Organization and the Department of Thai Traditional and Alternative Medicine (DTAM). Source: https://www.thaipbsworld.com/fah-talai-jone-proven-effective-in-improving-condition-of-covid-19-patients-dtam/

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D1 – An Insight into a Blockbuster Phytomedicine; Marrubium vulgare L. Herb. More of a Myth than a Reality?

Aerial parts and the root of Marrubium vulgare L. (white horehound) have been traditionally used in Europe and in southern and eastern Mediterranean countries. During colonization, the plant was introduced in America to great levels of popularity because of the simplicity of its growing; it was especially popular in Mexico and Brazil, where it has been known as ‘maromba’, ‘marroio’ or ‘marroio-branco’. Ethnopharmacological uses of M. vulgare include treating respiratory diseases such as acute or chronic bronchitis, colds and asthma. The plant is also used in cases where there is a lack of appetite or dyspepsia and for diagnosed type…

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E1 – Curcuma longa L. ameliorates asthma control in children and adolescents: A randomized, double-blind, controlled trial

Roots of Curcuma longa L. are used as medicine for millennia. They possess several pharmacological properties, including anti-inflammatory action, and can be suitable for asthma treatment. We aimed to test the hypothesis that, in children and adolescents with persistent asthma, the administration of powdered roots of C. longa for 6 months, in addition to standard treatment, compared to placebo, will result in better disease control. Patients and methods: We conducted a randomized, double-blind, placebo-controlled, phase II clinical trial. Patients were randomly assigned to receive 30 mg/kg/day of C. longa for 6 months, or placebo. Data were collected prospectively. All patients…

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E2 – Immunomodulatory activity of curcumin

Curcumin, an active ingredient present in Curcuma longa, was analysed for the immunomodulatory activity in Balb/c mice. Curcumin administration was found to increase the total WBC count (15,290) significantly on the 12th day Group of animals treated with vehicle alone showed results similar to that of normal animal (10,130 on 12th day). Curcumin increased the circulating antibody titre (512) against SRBC. Curcumin administration increased the plague forming cells (PFC) in the spleen and the maximum number of RFC was observed on the 6th day (1,130 PFC/10® spleen cells) after immunization with SRBC. Bone marrow cellularity (16.9×10 cells/femur) and a. -esterase…

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E6 – Curcumin Attenuates Allergen-Induced Airway Hyperresponsiveness in Sensitized Guinea Pigs

Curcumin Attenuates Allergen-Induced Airway Hyperresponsiveness in Sensitized Guinea Pigs Anti-asthmatic property of curcumin (diferuloylmethane), a natural product from the rhizomes of Curcuma longa, has been tested in a guinea pig model of airway hyperresponsiveness. We sensitized guinea pigs with ovalbumin (OVA) to develop certain characteristic features of asthma: allergen induced airway constriction and airway hyperreactivity to histamine. Guinea pigs were treated with curcumin during sensitization (to examine its preventive effect) or after developing impaired airways features (to examine its therapeutic effect). Status of airway constriction and airway hyperreactivity were determined by measuring specific airway conductance (SGaw) using a non-invasive technique,…

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E7 – Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kB inhibition

Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF‑kB inhibition Curcumin, a polyphenol compound from Curcuma longa L. has been used for centuries as an anti-inflammatory remedy including asthma. Curcumin has been reported to exert an anti-inflammatory effect, in part, through inhibition of the NF-kB pathway. The purposes of this study were to determine whether curcumin inhibits NF-kB dependent transcription in vitro, and test whether treatment with curcumin reduces allergen-induced airway inflammation and hyper-responsiveness in a mouse model of asthma through inhibition of NF-kB pathway. The effect of curcumin on NF-kB transcriptional activity was investigated using a cell-based…

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E8 – Curcumin (a constituent of turmeric): New treatment option against COVID-19

In late December 2019, the outbreak of respiratory illness emerged in Wuhan, China, and spreads worldwide. World Health Organization (WHO) named this disease severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused by a new member of beta coronaviruses. Several medications are prescribed to patients, and some clinical trials are underway. Scientists are trying to find a specific drug against this virus. In this review, we summarize the pathogenesis, clinical features, and current treatments of coronavirus disease 2019 (COVID-19). Then, we describe the possible therapeutic effects of curcumin and its molecular mechanism against coronavirus-19. Curcumin, as an active constituent of Curcuma…

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Epebetegségek, vírusfertőzések, szív- és érrendszeri betegségek enyhítése étrend-kiegészítőkkel

Dr. Várhalmi Antal Miklós 30 éve foglalkozik epesavakkal és az epe körforgással. Személyes érintettség okán és azzal a céllal, hogy más embereken is segítsen kb. 10 éve létrehozott egy természetes epesav tartalmú termékcsaládot. A GALLMET epesav kapszulák már sok-sok ember emésztési, és egyéb problémáin segítettek. Az epetermelés anomáliái, az epehiányos állapotok ugyanis gyakorlatilag az egész emésztésünkre és az egészségünkre is kihatnak. További információk: https://gallmet.hu/osszes-egeszsegugyi-javaslat/emesztes-es-epe-mukodes/ Ezután mivel az epesavak az immunrendszerre is jótékony hatással vannak, kifejlesztette az AntiBac készítményt. Ebben az epesavak mellett gyógynövények (bodza, fokhagyma, kurkuma, andrográfisz, fekete bors) találhatók, melyek segítenek a különböző fertőzések tüneteinek és mellékhatásainak enyhítésében. További…

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Hogyan segíthetnek az epesavak és a gyógynövények bakteriális és vírus fertőzések esetén?

Naturportal podcast 2022.08.31. Dr. Várhalmi Miklós epesavakkal és az enterohepatikus körfolyamatok kutatásával foglalkozik 30 éve.Epesavakkal kapcsolatos termékek fejlesztője. Mik az epesavak? Miben tudnak segíteni? Hogyan hatnak az epesavak az immunrendszerre? Hogyan segíthetnek az epesavak a vírusok és a baktériumok esetén? Miben segíthet az orvosi pemetefű, a fekete bodza, a fokhagyma, az andrográfisz, a kurkuma, a fekete bors és a komplexen? Milyen gyógynövény az andrográfisz? Segíthet-e ez a komplex szer a covid és más vírusok esetén? Milyen bakteriális fertőzésekben segíthet? A műsorvezetők: dr. Jung Andrea Naturportal Online Magazin: https://naturportal.hu/ Természetgyógyászok, pszichológusok, coach-ok, testi-lelki Segítők keresője: https://gyogyaszkereso.hu/ Császi András természetgyógyász, egészségfejlesztő https://vitalitasbolt.hu/

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Mit tehetünk különböző fertőzések tüneteinek enyhítésére és gyorsabb lefolyása érdekében?

A fertőzés kórokozók káros megtelepedését jelenti egy gazdaszervezetben. A fertőzéskor a fertőző organizmus a gazdaszervezet erőforrásait kívánja felhasználni annak érdekében, hogy szaporodjon. A fertőző élőlény a normálistól eltérő funkciót is okozhat, esetleg el is pusztíthatja a gazdaszervezetet. A baktérium és vírus fertőzések legjellemzőbb tünetei az alábbiak: láz, végtag- és ízületi fájdalom, orrfolyás, orrdugulás, torokfájás köhögés, tüsszögés fejfájás, gyengeség, levertség, hidegrázás, emésztési problémák (székrekedés vagy hasmenés), kiütések és egyéb bőrproblémák stb. Az orvos felkeresése és tanácsainak betartása mellett az alábbiak a legfontosabbak: lázcsillapítás, köhögés csillapítás, orrdugulás csökkentés, fájdalomcsillapítás, bő folyadék fogyasztás, megfelelő táplálkozás, vitamin – ásványi só – nyomelem pótlás stb….

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Epesavak közvetlen, vagy közvetett hatása: Hozzájárul a koleszterin szint csökkentéséhez

A1 – Antiviral properties of Elderberry

Sambucus nigra products (Sambucol) have antiviral properties against different strains of influenza virus. Sambucol Elderberry Extract and its formulations activate the healthy immune system by increasing inflammatory cytokine production. Standardized elderberry liquid extract possesses antimicrobial activity against both Gram-positive bacteria of Streptococcus pyogenes and group C and G Streptococci, and the Gram-negative bacterium Branhamella catarrhalis in liquid cultures. Sambucus Formosana Nakai stem ethanol extract displayed the strong anti-HCoV-NL63 (human coronavirus NL63) potential. Source:https://www.researchgate.net/publication/340236781_Antiviral_properties_of_Elderberry

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A3 – Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses

Black elderberries (Sambucus nigra L.) are well known as supportive agents against common cold and influenza. It is further known that bacterial super-infection during an influenza virus (IV) infection can lead to severe pneumonia. We have analyzed a standardized elderberry extract (Rubini, BerryPharma AG) for its antimicrobial and antiviral activity using the microtitre broth micro-dilution assay against three Gram-positive bacteria and one Gram-negative bacteria responsible for infections of the upper respiratory tract, as well as cell culture experiments for two different strains of influenza virus. The antimicrobial activity of the elderberry extract was determined by bacterial growth experiments in liquid…

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A4 – Randomized Study of the Efficacy and Safety of Oral Elderberry Extract in the Treatment of Influenza A and B Virus Infections

Randomized Study of the Efficacy and Safety of Oral Elderberry Extract in the Treatment of Influenza A and B Virus Infections The influenza virus is an orthomyxovirus and causes an acute respiratory tract disease. Influenza is typically characterized by abrupt onset of fever, headache, myalgia, sore throat and non-productive cough. The illness is usually self-limiting, with relief of symptoms occurring within 5 – 7 days. Nevertheless, it is an important disease due to its ease of communicability, short incubation time, rapid rate of viral mutation, related morbidity, resultant loss of productivity, and the possibility of severe complications. Influenza can be…

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A5 – Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers

Intercontinental air travel can be stressful, especially for respiratory health. Elderberries have been used traditionally, and in some observational and clinical studies, as supportive agents against the common cold and influenza. This randomized, double-blind placebo-controlled clinical trial of 312 economy class passengers travelling from Australia to an overseas destination aimed to investigate if a standardised membrane filtered elderberry (Sambucus nigra L.) extract has beneficial effects on physical, especially respiratory, and mental health. Cold episodes, cold duration and symptoms were noted in a daily diary and assessed using the Jackson score. Participants also completed three surveys containing questions regarding upper respiratory…

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A6 – Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama

Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama A standardized elderberry extract, Sambucol® (SAM), reduced hemagglutination and inhibited replication of human influenza viruses type A/Shangdong 9/93 (H3N2), A/Beijing 32/92 (H3N2), A/Texas 36/91 (HlNl), A/Singapore 6/86 (HlNl), type B/Panama 45/90, B/Yamagata 16/88, B/Ann Arbor 1/86, and of animal strains from Northern European swine and turkeys, A/Sw/Ger 2/81, A/Tur/Ger 3/91, and A/Sw/Ger 8533/91 in Madin–Darby canine kidney cells. A placebo-controlled, double blind study was carried out on a group of individuals living in…

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A9 – Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms

Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A metaanalysis of randomized, controlled clinical trials Upper respiratory symptoms are often treated with over the counter drugs, antibiotics, and antiviral medications. Due to concerns about safety and efficacy, there is a demand for an alternative solution. Black elderberry (Sambucus nigra) has been used to treat cold and flu symptoms, but there are no large-scale studies or meta-analyses. This meta-analysis quantifies the effects of elderberry supplementation and evaluates moderators including vaccination status and the underlying pathology. This analysis included a total of 180 participants and evaluates moderators such as vaccination…

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AntiBac összetevőinek élettani hatásai: epesavak, bodza, kurkuma, pemetefű, andrográfisz, fokhagyma

Szakértői beszélgetés az AntiBac kapszulák összetételéről és azok élettani hatásairól, melyek a következők: A fekete bodza támogatja az emberi szervezet védelmét biztosító immunrendszert. A fokhagyma hozzájárul a bél mikrobiológiai egyensúlyának a fenntartásához, valamint a káros baktériumok és mikroorganizmusok elleni védekezéshez. A keserű andrográfisz segíti a szervezet természetes védekező képességét, különösen a felső légutak szintjén. Az orvosi pemetefű segíti a béltraktust, hozzájárul az egészséges emésztéshez, a máj és epe normál működéséhez. A kurkuma + fekete bors segíti az immunrendszert, a tüdő és a légutak egészségét, valamint az allergiákkal szembeni védelmet, jelentős hatású antioxidáns. További információk a videóban! Forrás: D1 Tv –…

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B16 – Preventing the Common Cold With a Garlic Supplement

One hundred forty-six volunteers were randomized to receive a placebo or an allicin-containing garlic supplement, one capsule daily, over a 12-week period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. The active-treatment group had significantly fewer colds than the place­bo group (24 vs 65, P<.001). The placebo group, in contrast, recorded signifi­cantly more days challenged virally (366 vs 111, P<.005) and a significantly longer duration of symptoms (5.01 vs 1.52 days, P<.001). Consequently, volun­teers in the active group were less likely to get…

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B21, C10 – COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?

COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy? The outbreak of Coronavirus SARS-Cov-2 disease (COVID-19) in Wuhan (China) in late 2019 and its Worldwide spread has caused hundreds of thousands of deaths so far. As of July 2020, the disease seems to be mostly affecting Europe and the Americas. Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. Older people and those with underlying medical problems such as cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to develop serious illness…

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C12 – A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection

A randomized, double blind placebo controlled clinical study was conducted to evaluate the efficacy of KalmCold™, an extract of Andrographis paniculata, in patients with uncomplicated upper respiratory tract infection (URTI). The assessment involved quantification of symptom scores by Visual Analogue Scale. Nine self evaluated symptoms of cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance were scored. A total of 223 patients of both sexes were randomized in two groups which received either KalmCold™ (200 mg/day) or placebo in a double blind manner. In both the treatments, mean scores of all symptoms showed a decreasing trend…

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C13 – A randomized, controlled study of Kan Jang versus amantadine in the treatment of influenza in Volgograd

Two randomized, parallel-group clinical studies with a verum and a control group were performed to investigate the effect of a standardized extract (SHA-10) of Andrographis panaiculata (N.) fixed combination Kan Jang in the treatment of diagnosed influenza viral infection. The pilot study was performed on 540 patients with 71 Kan Jang-treated patients with the second phase conducted enrolling 66 patients. The differences in the duration of sick leave and frequency of post-influenza complications indicate that the Kan Jang phytopreparation not only contributes to quicker recovery, but also reduces the risk of post-influenza complications. Kan Jang was well tolerated by patients….

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C17 – Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children

Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children: A systematic review and meta-analysis Introduction: Antimicrobial resistance (AMR) is a substantial threat to public health. Safe and effective alternatives are required to reduce unnecessary antibiotic prescribing. Andrographis Paniculata (A. Paniculata, Chuān Xīn LiaÂn) has traditionally been used in Indian and Chinese herbal medicine for cough, cold and influenza, suggesting a role in respiratory tract infections (RTIs). This systematic review aimed to evaluate the clinical effectiveness and safety of A. Paniculata for symptoms of acute RTIs (ARTIs). Results: Thirty-three RCTs (7175 patients) were…

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D1 – An Insight into a Blockbuster Phytomedicine; Marrubium vulgare L. Herb. More of a Myth than a Reality?

Aerial parts and the root of Marrubium vulgare L. (white horehound) have been traditionally used in Europe and in southern and eastern Mediterranean countries. During colonization, the plant was introduced in America to great levels of popularity because of the simplicity of its growing; it was especially popular in Mexico and Brazil, where it has been known as ‘maromba’, ‘marroio’ or ‘marroio-branco’. Ethnopharmacological uses of M. vulgare include treating respiratory diseases such as acute or chronic bronchitis, colds and asthma. The plant is also used in cases where there is a lack of appetite or dyspepsia and for diagnosed type…

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Epesavak közvetlen, vagy közvetett hatása: Közreműködik a pikkelysömör (psoriasis) enyhítésében

C12 – A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection

A randomized, double blind placebo controlled clinical study was conducted to evaluate the efficacy of KalmCold™, an extract of Andrographis paniculata, in patients with uncomplicated upper respiratory tract infection (URTI). The assessment involved quantification of symptom scores by Visual Analogue Scale. Nine self evaluated symptoms of cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance were scored. A total of 223 patients of both sexes were randomized in two groups which received either KalmCold™ (200 mg/day) or placebo in a double blind manner. In both the treatments, mean scores of all symptoms showed a decreasing trend…

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Magyar és nemzetközi szakirodalom és alkalmazási területek

A hivatalos magyar és nemzetközi szakirodalom sokrétűen foglalkozik a termékben lévő összetevők hatóanyagaival kapcsolatos elméleti alapokkal, tudományos vizsgálatokkal, gyakorlati tapasztalatokkal. A tudatos fogyasztó számára kötelező tájékoztatást adnunk arról, amit megvásárol. Jelen tájékoztató a fogyasztók megfelelő és teljeskörű tájékoztatását, valamint a megalapozott és tudatos fogyasztói döntés segítését szolgálja az epesavak és a gyógynövények élettani hatásaira vonatkozó szakirodalom vázlatos bemutatásával. Jelen tájékoztató összeállítása során mindenben a fogyasztóvédelemről szóló 1997. évi CLV. törvény használati és kezelési útmutatóra vonatkozó rendelkezései, az élelmiszerláncról és hatósági felügyeletéről szóló 2008. évi XLVI. törvény élelmiszerek címkézésére vonatkozó rendelkezései és a fogyasztókkal szembeni tisztességtelen kereskedelmi gyakorlat tilalmáról szóló 2008. évi XLVII. törvény általános előírásai valamint EU 2000/13/EK és 1924/2006/EK irányelvek illetve rendeletek szerint jártunk el, szem előtt tartva a jogszabályok azon törekvését, hogy a fogyasztó a lehető legteljesebb és legrészletesebb információval rendelkezzen az általa megvásárolni szándékozott vagy már megvett termékkel és annak hatóanyagaival kapcsolatosan. A termék alapanyagaival kapcsolatos információk ismeretterjesztő célzatúak, nem utalnak a termékkel kapcsolatos összhatásokra, amit célzottan a terméktájékoztatóban találnak meg.

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