Symptoms, and indirect or direct effects of the active substances
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Direct or indirect effect of bile acids: Contribute to the relief of allergic complaints
Direct or indirect effect of bile acids: Play a role in relieving insomnia, sleep disturbance and concentration disorders
AntiBac capsules in brief: boosting immunity, alleviating side effects and complications of infections - video
Short presentation of Dr. Antal Miklós Várhalmi, developer of AntiBac food supplements at the WFC Hungary Conference 2021.05.08.
B2 - Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data
Garlic (Allium sativum L.) is a common herb consumed worldwide as functional food and traditional remedy for the prevention of infectious diseases since ancient time. Garlic and its active organosulfur compounds (OSCs) have been reported to alleviate a number of viral infections in pre-clinical and clinical investigations. However, so far no systematic review on its antiviral effects and the underlying molecular mechanisms exists. The aim of this review is to systematically summarize pre-clinical and clinical investigations on antiviral effects of garlic and its OSCs as well as to further analyse recent findings on the mechanisms that underpin these antiviral actions....
B3 - Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review
Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an aromatic herbaceous plant that is consumed worldwide as food and traditional remedy for various diseases. It has been reported to possess several biological properties including anticarcinogenic, antioxidant, antidiabetic, renoprotective, anti-atherosclerotic, antibacterial, antifungal, and antihypertensive activities in traditional medicines. A. sativum is rich in several sulfur-containing phytoconstituents such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids such as quercetin. Extracts and isolated compounds of A. sativum have been evaluated for various biological activities...
B4 - Assessment report on Allium sativum L., bulbus
Description of the herbal substance(s), herbal preparation(s) or combinations thereof. The aim of this report is to assess the non-clinical and clinical data available on Allium sativum for preparing a European Union herbal monograph. This report is based on the documentation published in the literature.Herbal substance(s) The composition of Allium bulbus is complex. Garlic contains volatile oil (0.1-0.36%), the major components are sulphur compounds like alliin, it also contains proteins (amino acids, glutamyl peptides...), glucides, enzymes (alliinase, peroxidase, myronidase...) Allicin is formed from alliin by the alliinase. It is considered that 1 mg of alliin is equivalent to 0.45 mg...
D3 - Marrubium vulgare L.: A Phytochemical and Pharmacological Overview
Marrubium vulgare is a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies, M. vulgare acts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+bacteria, fungi, herpes simplex virus, and parasites such as Toxoplasma gondii, Trichomonas vaginalis, and Plasmodium berghei-berghei was recorded. Additionally, it...
D5 - Evaluation of In Vitro Antioxidant and In Vivo Anti-inflammatory Potential of White Horehound (Marrubium vulgare L) Leaves
The present study was designed to explore the anti-inflammatory effect and antioxidant potential of the methanolic extract of Marrubium vulgare leaves, a popular traditional medicinal herb. In vivo anti-inflammatory activity was evaluated by the paw edema assay induced by carrageenin in rat model, while antioxidant activity was evaluated by two tests: assay of free radical-scavenging activity on DPPH and Ferric reducing antioxidant plasma (FRAP). Total phenolic and total flavonoid contents of the crude methanolic extract were also determined by Folin-Ciocalteu's phenol reagent and by aluminium chloride method, respectively. The results showed that methanol extract had high level of polyphenols (195...
D6 - A methanolic extract of Marrubium vulgareL. suppresses inflammatory responses in isoproterenol induced myocardial infarction in rat
Marrubium vulgare (Lamiaceae) is a medicinal herb and have been shown to have strong anti-inflammatory activities. The aim of the present study was to investigate the cardio protective effects of the methanolic extract of the plant on isoproterenol-induced acute myocardial infarction (MI). It is well known that inflammation plays a key role in the development of cardiovascular diseases. The results of our study demonstrated that a methanolic extract of Marrubium vulgare has strong protective effects against isoproterenol-induced myocardial infarction and this protection possibly is mediated through its anti-inflammatory actions. Source:http://www.rps.mui.ac.ir/index.php/jrps/article/view/977/961
Dr János Medgyesi: how to beat the corona virus in two days
Dr János Medgyesi, a general practitioner, achieved a significant result within 2 days of treating the COVID infection he had caught. After 48 hours of a positive coronavirus test, another test showed a negative result and his treatment instructions are as follows. Avoid fruit, sweets and carbohydrates if possible. Give bile acid to the body, as the coronavirus has a fatty membrane and fat is broken down by bile. Take a smooth muscle antispasmodic to help empty the gallbladder. Plenty of rest, preferably sleep. @medfood_diet #healing #covid #fyp #doctor #stress #vegetative #lifestyle #medfood #radiography ♬ original voice - Dr János Medgyesi...
E11 - Efficacy of Curcumin as Adjuvant Therapy to Induce or Maintain Remission in Ulcerative Colitis Patients: an Evidence-based Clinical Review
Treatment guidelines for ulcerative colitis (UC) not yet established. Currently, mesalazine, corticosteroids, and immunomodulators are treatment options for UC. However, they are known to have unpleasant side effects such as nausea, vomiting, headaches, hepatitis, and male infertility. Curcumin is found in Turmeric plants (Curcuma longa L.), which possesses both anti-inflammatory and antioxidant properties. This study aimed to determine whether curcumin as adjuvant therapy can induce or maintain remission in UC patients. Structured search in three databases (Cochrane, PubMed, Proquest) using "curcumin", "remission" and "Ulcerative Colitis" as keywords. Inclusion criteria is randomized controlled trials (RCTs), meta-analysis, or systematic review using curcumin...
E2 - Immunomodulatory activity of curcumin
Curcumin, an active ingredient present in Curcuma longa, was analysed for the immunomodulatory activity in Balb/c mice. Curcumin administration was found to increase the total WBC count (15,290) significantly on the 12th day Group of animals treated with vehicle alone showed results similar to that of normal animals (10,130 on 12th day). Curcumin increased the circulating antibody titre (512) against SRBC. Curcumin administration increased the plague forming cells (PFC) in the spleen and the maximum number of RFC was observed on the 6th day (1,130 PFC/10® spleen cells) after immunization with SRBC. Bone marrow cellularity (16.9×10 cells/femur) and a. -esterase...
G5 - Assessment report on Sambucus nigra L., fructus
Description of the herbal substance(s), herbal preparation(s) or combinations therefore. Herbal substance(s) The herbal substance consists of the dried, ripe berries of Sambucus nigra L. (elderberry). The wrinkled, more or less spherical drops are dark violet-black and slightly glossy with a size around 0.5 cm. Usually, they contain three, somewhat elongated stones, each of which has a seed inside the hard endocarp. Fruit stalks are occasionally present. Elderberry belongs to the family Caprifoliaceae (Wichtl 2004). Elder berries taste sweet and sourish with a characteristic aroma (Bisset and Wichtl 2001, Wichtl 2004, Hiermann 2010). Two clinical studies have been conducted by...
What motivated the development of AntiBac capsules? To protect against side effects and complications of infections
A short discussion about AntiBac capsules, which were developed motivated by the following:Current infection period Further development of the GALLMET capsule experience Supporting the human body's defences with bile acids and herbs More information in the video! D1 Tv - Vitality 2021.05.28.Béky László László naturopath and Dr. Antal Miklós Várhalmi Antal product developer
Newsletter 9: Autumn is here, and it's that time again... for respiratory infections
🦠 If you or someone you care about is experiencing symptoms similar to a cold, the most important things to do are to see a doctor and follow his or her advice: stop fever, stop coughing, relieve pain, eat right, drink plenty of fluids, etc. (and we're not talking about a hat cure). In addition to the above, vitamins C and D, herbs known from folk medicine and scientific research are also effective in alleviating the symptoms of various bacterial and viral infections and colds, and in speeding up their progress, the most important of which are also included in AntiBac 💊. 🧄 Garlic: one capsule of GALLMET-Immun (AntiBac) contains the active ingredient of several cloves of garlic, which inhibits the multiplication of many respiratory pathogens (bacteria, viruses)
The seven ingredients of AntiBac relieve the symptoms of colds, flus and flu both individually and synergistically!
'A cold, or cold, or rhinitis, is a viral infection of the upper respiratory tract that primarily attacks the mucous membranes of the nose and throat, but can also appear in the lungs. There is no precise scientific or medical definition of a cold (the only thing to do with colds is that pathogens are seasonally more active in winter). The most common pathogen is rhinovirus, but it can be caused by more than 200 different viruses and sometimes bacterial infection can aggravate symptoms. Colds are often mistaken for the much more serious flu. Colds are the most common type of infection in humans. Symptoms include cough, sore throat, runny nose and fever, depending on severity and extent. A...
A1 - Antiviral properties of Elderberry
Sambucus nigra products (Sambucol) have antiviral properties against different strains of influenza virus. Sambucol Elderberry Extract and its formulations activate the healthy immune system by increasing inflammatory cytokine production. Standardized elderberry liquid extract possesses antimicrobial activity against both Gram-positive bacteria of Streptococcus pyogenes and group C and G Streptococci, and the Gram-negative bacterium Branhamella catarrhalis in liquid cultures. Sambucus Formosana Nakai stem ethanol extract displayed the strong anti-HCoV-NL63 (human coronavirus NL63) potential. Source:https://www.researchgate.net/publication/340236781_Antiviral_properties_of_Elderberry
A3 - Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses
Black elderberries (Sambucus nigra L.) are well known as supportive agents against common cold and influenza. It is further known that bacterial super-infection during an influenza virus (IV) infection can lead to severe pneumonia. We have analyzed a standardized elderberry extract (Rubini, BerryPharma AG) for its antimicrobial and antiviral activity using the microtitre broth micro-dilution assay against three Gram-positive bacteria and one Gram-negative bacteria responsible for infections of the upper respiratory tract, as well as cell culture experiments for two different strains of influenza virus. The antimicrobial activity of the elderberry extract was determined by bacterial growth experiments in liquid...
A9 - Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms
Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: a meta-analysis of randomized, controlled clinical trials Download - PDF Abstract Upper respiratory symptoms are often treated with over the counter drugs, antibiotics, and antiviral medications. Due to concerns about safety and efficacy, there is a demand for an alternative solution. Black elderberry (Sambucus nigra) has been used to treat cold and flu symptoms, but there are no large-scale studies or meta-analyses. This meta-analysis quantifies the effects of elderberry supplementation and evaluates moderators including vaccination status and the underlying pathology. This analysis included a total of 180 participants and evaluates
AntiBac capsules in brief: boosting immunity, alleviating side effects and complications of infections - video
Short presentation of Dr. Antal Miklós Várhalmi, developer of AntiBac food supplements at the WFC Hungary Conference 2021.05.08.
Physiological effects of the AntiBac ingredients: bile acids, elderberry, turmeric, white horehound, king of bitter, garlic
An expert discussion on the composition of AntiBac capsules and their physiological effects, which include: black elderberry supports the immune system to protect the human body. Garlic helps to maintain the microbiological balance of the gut and to defend against harmful bacteria and microorganisms. Bitter andrographis helps the body's natural defences, particularly at the level of the upper respiratory tract. Medicinal orchid helps the intestinal tract, contributing to healthy digestion and the normal functioning of the liver and bile. Turmeric + Black Pepper supports the immune system, lung and respiratory tract health and protection against allergies, it is a powerful antioxidant. More information in the video! Source: D1 Tv -...
The role of digestion and bile function in the proper functioning of the immune system and in the defence against infections
Source: Zöld Újság December 2021 In the stomach, hydrochloric acid helps to neutralise and break down many bacteria, viruses, fungi and micro-organisms, which is a great help for our immune system, but we can also help to protect our health by paying attention to the proper cycle of bile acids of our body. In the lower intestinal tract, bile and bile acids also have an antiseptic effect, and if there is not enough bile produced, these antiseptic functions will not work properly. In the current infection season, we can support our immune system not only by absorbing the food we eat and getting enough vitamins into our bodies. Most of the arrowheads are located in the intestinal wall and around the intestinal tract, which have the...
B13 - The association of garlic with Helicobacter pylori infection and gastric cancer risk
Background Garlic may be protective against Helicobacter pylori infection and gastric cancer development. We conducted this study to quantitatively update evidence on garlic intake and gastric cancer with the inclusion of most recent cohort studies and qualitatively summarize epidemiological studies of garlic consumption and Helicobacter pylori infection. Materials and methods PubMed, Embase, MEDLINE, and Cochrane Library were searched on April 2018. We conducted a meta-analysis to determine whether garlic intake reduced gastric cancer risk using random-effect models and a systematic review to summarize evidence on the association between garlic consumption and Helicobacter pylori infection. Risk of bias was assessed using...
B15 - Review: antimicrobial properties of allicin used alone or in combination with other medications
Garlic (Allium sativum L.) is a well-known spice widely utilised for its medicinal properties. There is an extensive record of the many beneficial health effects of garlic which can be traced back to as early as the ancient Egyptian era. One of the most studied properties of garlic is its ability to cure certain ailments caused by infections. In the 1940s, the antimicrobial activities exhibited by garlic were first reported to be due to allicin, a volatile compound extracted from raw garlic. Since then, allicin has been widely investigated for its putative inhibitory activities against a wide range of microorganisms....
B17 - Plants of the genus Allium as antibacterial agents: from tradition to pharmacy
Plants belonging to the genus Allium are widely cultivated and used all over the world as food and medicinal plants. Since ancient times, these plants, particularly garlic (Allium sativum L.) and onion (Allium cepa L.), have represented important components of typical recipes and traditional healing systems. Not the least of which, their use as food biopreservatives is well documented, due to the relevant antibacterial activity of their extracts and essential oils. In addition to garlic and onion, this review article deals with the main members of the genus Allium, including A. ampeloprasum (Leek), A. schoenoprasum (Chive) and A. ascalonicum (Shallot),...
B2 - Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data
Garlic (Allium sativum L.) is a common herb consumed worldwide as functional food and traditional remedy for the prevention of infectious diseases since ancient time. Garlic and its active organosulfur compounds (OSCs) have been reported to alleviate a number of viral infections in pre-clinical and clinical investigations. However, so far no systematic review on its antiviral effects and the underlying molecular mechanisms exists. The aim of this review is to systematically summarize pre-clinical and clinical investigations on antiviral effects of garlic and its OSCs as well as to further analyse recent findings on the mechanisms that underpin these antiviral actions....
B3 - Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review
Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an aromatic herbaceous plant that is consumed worldwide as food and traditional remedy for various diseases. It has been reported to possess several biological properties including anticarcinogenic, antioxidant, antidiabetic, renoprotective, anti-atherosclerotic, antibacterial, antifungal, and antihypertensive activities in traditional medicines. A. sativum is rich in several sulfur-containing phytoconstituents such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids such as quercetin. Extracts and isolated compounds of A. sativum have been evaluated for various biological activities...
B8 - Garlic intake and the risk of colorectal cancer A meta-analysis
Garlic intake and the risk of colorectal cancer A meta-analysis Download - PDF Abstract This was a meta-analysis of epidemiological articles that aimed to estimate the association of garlic intake with the risk of colorectal cancer (CRC). Electronic databases, including the Cochrane Database of Systematic Reviews, PubMed, and EMBASE, were systemically searched from inception to May 2019 to identify related articles. In addition, a random model was used to pool the included evidence based on heterogeneity. Additionally, subgroup analyses were carried out to examine the differences between different groups. The stability of our findings was tested through sensitivity analyses. Publication
D2 - Phytochemical screening and antiviral activity of Marrubium vulgare
Introduction Aims: The present study is to investigate the phytochemical content, cytotoxicity and antiviral activity of the crude and fractions from Marrubium vulgare. Methodology and results: The crude methanol extract and fractions using hexane, chloroform, ethyl acetate and n-butanol of M. vulgare whole plant were produced in this study. Qualitative phytochemical analysis revealed the presence of flavones aglycones and steroid in all preparations except for the hexane fraction. Carbohydrates, saponins were found present in the crude and ethyl acetate extracts while tannin was detected in the crude, ethyl acetate and butanol extracts. Anthraquinones and terpenes were detected in the hexane...
D3 - Marrubium vulgare L.: A Phytochemical and Pharmacological Overview
Marrubium vulgare is a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies, M. vulgare acts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+bacteria, fungi, herpes simplex virus, and parasites such as Toxoplasma gondii, Trichomonas vaginalis, and Plasmodium berghei-berghei was recorded. Additionally, it...
D4 - Chemical Characterization and Antibacterial Activity of Phases Obtained from Extracts of Artemisia herba alba, Marrubium vulgare and Pinus pinaster
Chemical Characterization and Antibacterial Activity of Phases Obtained from Extracts of Artemisia herba alba, Marrubium vulgare and Pinus pinaster Download - PDF Abstract The objective of this study is the phytochemical characterization and antibacterial activity of Artemisia herba alba, Marrubium vulgare and Pinus pinaster. The antibacterial potential of different fractions of ethyl acetate, diethyl ether and 1 butanol extracts of the three plants were tested on four strains of bacteria: Staphylococcus aureus, Escherichia coli, Proteus vulgaris and Pseudomonas aeruginosa. The results of phytochemical screening showed a rich and varied composition of secondary metabolites: flavonoids, tannins, terpenes, sterols, coumarins and saponins
Dr János Medgyesi: how to beat the corona virus in two days
Dr János Medgyesi, a general practitioner, achieved a significant result within 2 days of treating the COVID infection he had caught. After 48 hours of a positive coronavirus test, another test showed a negative result and his treatment instructions are as follows. Avoid fruit, sweets and carbohydrates if possible. Give bile acid to the body, as the coronavirus has a fatty membrane and fat is broken down by bile. Take a smooth muscle antispasmodic to help empty the gallbladder. Plenty of rest, preferably sleep. @medfood_diet #healing #covid #fyp #doctor #stress #vegetative #lifestyle #medfood #radiography ♬ original voice - Dr János Medgyesi...
I also had a gall bladder operation, I have been carrying Giardia ever since.
Dear GALLMET! I have also had an operation for bile. It has been 20 years. I have supposedly been carrying Giardia ever since. I just finished the treatment and have to go back for another test. My life is a nightmare with nausea and diarrhea. Can you suggest something? T.I. Dear T.I.! We recommend that you try a course of the AntiBac preparation available from our webshop. This means taking 3×1 capsules a day for 10 days with a normal diet at the start of meals. When you have finished this, you can continue using GALLMET-Natural. Please write to us after the AntiBac cure to see if you feel any change, what your experience has been, and if we can help you further. GALLMED Ltd.
Alleviating biliary diseases, viral infections, cardiovascular diseases with food supplements
Dr. Antal Miklós Várhalmi has been working with bile acids and the cycle of bile acids for 30 years. Due to personal involvement and with the aim of helping other people, he created a range of products containing natural bile acids about 10 years ago. GALLMET bile acid capsules have helped many people with digestive and other problems. Abnormalities in bile production and bile deficiency can affect our digestion and health. For more information: https://gallmet.hu/osszes-egeszsegugyi-javaslat/emesztes-es-epe-mukodes/ Then, because bile acids are also good for the immune system, he developed AntiBac. In addition to bile acids, it contains herbs (elderberries, garlic, turmeric, androgyrosis, black pepper) that help to alleviate the symptoms and side effects of various infections. More...
The role of bile acids in the physio-chemical protection of the body - AntiBac capsules
Expert discussion about the AntiBac capsule, to the development of which the following Hungarian literature contributed significantly: the research of Professor Lóránd Dr Bertók: Physico-chemical protection based on the detergent (fat-reducing) effect of bile acids Dr Péter Hegyi: New approaches in bile acid therapy More information in the video! Place of publication: D1 Tv - Vitalitás 28.05.2021. Béky László Naturopath and Dr Antal Miklós Várhalmi Developer
Relieving the symptoms of infections with herbs and bile acids: AntiBac capsules
A short discussion on AntiBac capsules, a further development of the GALLMET bile acid capsules. Based on Hungarian and international scientific research, bile acids provide protection against harmful bacteria and lipid-coated macro viruses. The other ingredients are. Garlic contributes to the maintenance of the microbiological balance of the intestine and to the protection against harmful bacteria and microorganisms. Bitter andrographis helps the body's natural defences, particularly at the level of the upper respiratory tract. Medicinal orchid helps the intestinal tract, contributing to healthy digestion and the normal functioning of the liver and bile. Turmeric + black pepper supports the immune system,...
G10 - Gram-negative versus Gram-positive bacteremia: which is more alarmin(g)?
Gram-negative bacteremia has been associated with severe sepsis, although the exact mechanism and pathophysiological diff erences among bacterial species are not well understood. In the previous issue of Critical Care, Abe and colleagues report results of a retrospective study that show a significantly higher incidence of Gram-negative bacteremia among adult intensive care unit patients with septic shock than in those with sepsis or severe sepsis. In this study, C-reactive protein and IL-6 levels were significantly higher in Gram-negative bacteremia than in Gram-positive bacteremia. These observations suggest a distinct immunopathophysiological behaviour of sepsis in patients with Gram-negative bacteremia that...
G16 - Physiological effects of endotoxin
The physiological role of endotoxin in humans is multifaceted and dose-dependent. We now know that endotoxins only exert their effects when released from the surface of Gram-negative bacteria. This can happen when the bacterium dies or when it starts to multiply. Normally, millions of Gram-negative bacteria live in the mammalian body and do not cause any health problems. In pathological cases, endotoxemia occurs as a result of large amounts of endotoxin entering the bloodstream, which can cause trauma and shock. Endotoxins act mainly through macrophages. These cells, which play a protective role, normally absorb and break down substances harmful to the body. Live or dead bacteria...
G17 - Gram negative sepsis and shock
In the modern hospital gram negative bacteremia and the associated condition of septic shock are common occurrences. In the United States the estimated incidence of gram negative bacteremia ranges from 71,000 to 330,000 cases annually. Fatalities attributed to this disease are between 18,000 and 132,000 each year. Sepsis is defined as a systemic disease caused by microorganisms or their products in the blood. Bacteremia is the presence of viable organisms in the circulation. Gram negative bacteremia in the critically ill patient is synonymous with gram negative sepsis. Septic shock is a clinical syndrome characterized by circulatory insufficiency and inadequate tissue...
G18 - Changes in the prevalence of multi-drug resistant pathogens and implications for the ICU
Incidence of nosocomial infections and antibiotic resistance in intensive care units is increasing worldwide. Blood-stream infections of Gram-negative non-fermentative bacteria are associated with higher mortality. The aim of this study was to compare the antibiotic sensitivity of nosocomial blood-stream infections between years 2008-2010. There was no difference in the sensitivity of methycillin-resistant Staphylococcus aureus and extended-spectrum beta lactamase producing Klebsiella spp. and Escherichia coli infections between the two years examined. Antibiotic resistance of Acinetobacter baumannii and Pseudomonas infections showed a marked increase in 2010 when compared to that found in 2008: there was no multiresistant Acinetobacter infection in samples obtained...
G9 - Gram-Negative Sepsis: a Dilemma of Modern Medicine
Gram-negative sepsis, a relatively rare clinical diagnosis only a few decades ago, is perhaps the most important infectious disease problem in hospitals today. Despite recent advances in our understanding of the pathophysiological mechanisms of sepsis and improved antimicrobial therapy, the mortality rate from gram-negative sepsis remains frustratingly high, particularly after the onset of shock. Unfortunately, many of the therapeutic methods proposed over the years for the management of sepsis and its complications have either failed to meet their initial expectations or remain unproven, despite many anecdotal reports. Recently, however, the development of new monoclonal antibodybased treatments, together with earlier recognition...
How does AntiBac work? Which bacteria is it effective against?
A brief discussion about AntiBac capsules, which work as follows: the ingredients have been selected based on international scientific research to protect against certain harmful bacteria. The active ingredients of the ingredients act on the body's entire immune system. In addition to their individual effects, they also have a beneficial effect on complications of various infections, such as fever, cough, limb pain, etc. D1 Tv - Vitality 2021.05.28.Béky László László naturopath and Dr. Antal Miklós Várhalmi Antal product developer
How can bile acids and herbs help with bacterial and viral infections?
Naturportal podcast 2022.08.31. Dr. Miklós Várhalmi has been working with bile acids and enterohepatic circuits for 30 years. Developer of bile acid related products. What are bile acids? What can they do for you? How do bile acids affect the immune system? How can bile acids help with viruses and bacteria? What can medical pemethrum, black elderberry, garlic, andrographis, turmeric, black pepper and complexene help with? What herb is andrographis? Can this complex help with covid and other viruses? What bacterial infections can it help with? Presenters.
What motivated the development of AntiBac capsules? To protect against side effects and complications of infections
A short discussion about AntiBac capsules, which were developed motivated by the following:Current infection period Further development of the GALLMET capsule experience Supporting the human body's defences with bile acids and herbs More information in the video! D1 Tv - Vitality 2021.05.28.Béky László László naturopath and Dr. Antal Miklós Várhalmi Antal product developer
How is Gallmet Immune (AntiBac) different from Natural and Mix? Comprehensive action to support the immune system
A discussion about AntiBac capsules, showing how AntiBac is different from GALLMET: AntiBac's ingredients act synergistically on the human body, while GALLMET mainly acts on the digestive system More information in the video! Source: D1 Tv - Vitality 2021.05.28. László Béky naturopath and Dr Antal Miklós Várhalmi product developer.
What can be done to relieve the symptoms of various infections and help them to go away more quickly?
Infection means the harmful colonisation of a host by pathogens. In infection, the infecting organism seeks to use the resources of the host to reproduce. The infecting organism may also cause abnormal function and possibly destroy the host. The most common symptoms of bacterial and viral infections are: fever, limb and joint pain, runny nose, nasal congestion, sore throat, cough, sneezing, headache, weakness, lethargy, chills, digestive problems (constipation or diarrhoea), rashes and other skin problems, etc. In addition to consulting a doctor and following his/her advice, the most important things to do are: relieving fever, cough, nasal congestion, pain relief, drinking plenty of fluids, eating right, taking vitamins and minerals, trace elements, etc.
Direct or indirect effect of bile acids: Play a role in the relief of IBS (Irritable Bowel Syndrome, Enterocolitis, Crohn's disease, small bowel inflammation, ulcerative colitis, duodenitis, polyps and colon cancer.
Direct or indirect effect of bile acids: Playing a role in alleviating diabetes
Direct or indirect effect of bile acids: Play a role in alleviating cancer
Direct or indirect effect of bile acids: Contributes to the alleviation of obesity.
Direct or indirect action of bile acids: aid digestion - fat digestion - relieve bloating
Digestive support - breaking down fats with bile acidsEffect of bile acids
Direct or indirect effect of bile acids: Support in case of gallbladder surgery
C12 - A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection
A randomized, double blind placebo controlled clinical study was conducted to evaluate the efficacy of KalmCold™, an extract of Andrographis paniculata, in patients with uncomplicated upper respiratory tract infection (URTI). The assessment involved quantification of symptom scores by Visual Analogue Scale. Nine self-evaluated symptoms of cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance were scored. A total of 223 patients of both sexes were randomized in two groups which received either KalmCold™ (200 mg/day) or placebo in a double blind manner. In both the treatments, mean scores of all symptoms showed a decreasing trend...
Direct or indirect action of bile acids: Contributes to mitigating the effects of fungal infections, plays a role in maintaining good gut bacteria levels
E15 - Vasodilating, spasmolytic, inotropic and chronotropic activities of curcuminoids from Curcuma longa in isolated organ preparations of guinea pigs
Turmeric is a yellowish orange spice, widely used in Asian cuisine and obtained from the rhizome of Curcuma longa. It is a mixture of three curcuminoids namely, curcumin, demethoxycurcumin and bisdemethoxycurcumin. Turmeric has been used as a medicinal substance since ancient times for respiratory and gastrointestinal problems. The aim of the present study was to investigate which curcuminoid contributes to the observed pharmacological activities, all three curcuminoids, the major curcumin metabolite tetrahydrocurcumin, and the non-enzymatic curcumin hydrolysis products ferulic acid, feruloyl methane and vanillin were analyzed for spasmolytic, inotropic and chronotropic activity. Furthermore, their uptake in respective tissue samples was...
A1 - Antiviral properties of Elderberry
Sambucus nigra products (Sambucol) have antiviral properties against different strains of influenza virus. Sambucol Elderberry Extract and its formulations activate the healthy immune system by increasing inflammatory cytokine production. Standardized elderberry liquid extract possesses antimicrobial activity against both Gram-positive bacteria of Streptococcus pyogenes and group C and G Streptococci, and the Gram-negative bacterium Branhamella catarrhalis in liquid cultures. Sambucus Formosana Nakai stem ethanol extract displayed the strong anti-HCoV-NL63 (human coronavirus NL63) potential. Source:https://www.researchgate.net/publication/340236781_Antiviral_properties_of_Elderberry
A3 - Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses
Black elderberries (Sambucus nigra L.) are well known as supportive agents against common cold and influenza. It is further known that bacterial super-infection during an influenza virus (IV) infection can lead to severe pneumonia. We have analyzed a standardized elderberry extract (Rubini, BerryPharma AG) for its antimicrobial and antiviral activity using the microtitre broth micro-dilution assay against three Gram-positive bacteria and one Gram-negative bacteria responsible for infections of the upper respiratory tract, as well as cell culture experiments for two different strains of influenza virus. The antimicrobial activity of the elderberry extract was determined by bacterial growth experiments in liquid...
G10 - Gram-negative versus Gram-positive bacteremia: which is more alarmin(g)?
Gram-negative bacteremia has been associated with severe sepsis, although the exact mechanism and pathophysiological diff erences among bacterial species are not well understood. In the previous issue of Critical Care, Abe and colleagues report results of a retrospective study that show a significantly higher incidence of Gram-negative bacteremia among adult intensive care unit patients with septic shock than in those with sepsis or severe sepsis. In this study, C-reactive protein and IL-6 levels were significantly higher in Gram-negative bacteremia than in Gram-positive bacteremia. These observations suggest a distinct immunopathophysiological behaviour of sepsis in patients with Gram-negative bacteremia that...
G17 - Gram negative sepsis and shock
In the modern hospital gram negative bacteremia and the associated condition of septic shock are common occurrences. In the United States the estimated incidence of gram negative bacteremia ranges from 71,000 to 330,000 cases annually. Fatalities attributed to this disease are between 18,000 and 132,000 each year. Sepsis is defined as a systemic disease caused by microorganisms or their products in the blood. Bacteremia is the presence of viable organisms in the circulation. Gram negative bacteremia in the critically ill patient is synonymous with gram negative sepsis. Septic shock is a clinical syndrome characterized by circulatory insufficiency and inadequate tissue...
G18 - Changes in the prevalence of multi-drug resistant pathogens and implications for the ICU
Incidence of nosocomial infections and antibiotic resistance in intensive care units is increasing worldwide. Blood-stream infections of Gram-negative non-fermentative bacteria are associated with higher mortality. The aim of this study was to compare the antibiotic sensitivity of nosocomial blood-stream infections between years 2008-2010. There was no difference in the sensitivity of methycillin-resistant Staphylococcus aureus and extended-spectrum beta lactamase producing Klebsiella spp. and Escherichia coli infections between the two years examined. Antibiotic resistance of Acinetobacter baumannii and Pseudomonas infections showed a marked increase in 2010 when compared to that found in 2008: there was no multiresistant Acinetobacter infection in samples obtained...
G9 - Gram-Negative Sepsis: a Dilemma of Modern Medicine
Gram-negative sepsis, a relatively rare clinical diagnosis only a few decades ago, is perhaps the most important infectious disease problem in hospitals today. Despite recent advances in our understanding of the pathophysiological mechanisms of sepsis and improved antimicrobial therapy, the mortality rate from gram-negative sepsis remains frustratingly high, particularly after the onset of shock. Unfortunately, many of the therapeutic methods proposed over the years for the management of sepsis and its complications have either failed to meet their initial expectations or remain unproven, despite many anecdotal reports. Recently, however, the development of new monoclonal antibodybased treatments, together with earlier recognition...
Direct or indirect action of bile acids: Supports the immune system, contributes to natural resistance, physico-chemical defence / bactericidal and antiviral action
Direct or indirect action of bile acids: relieving reflux and gastric acid overload
B2 - Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data
Garlic (Allium sativum L.) is a common herb consumed worldwide as functional food and traditional remedy for the prevention of infectious diseases since ancient time. Garlic and its active organosulfur compounds (OSCs) have been reported to alleviate a number of viral infections in pre-clinical and clinical investigations. However, so far no systematic review on its antiviral effects and the underlying molecular mechanisms exists. The aim of this review is to systematically summarize pre-clinical and clinical investigations on antiviral effects of garlic and its OSCs as well as to further analyse recent findings on the mechanisms that underpin these antiviral actions....
B3 - Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review
Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an aromatic herbaceous plant that is consumed worldwide as food and traditional remedy for various diseases. It has been reported to possess several biological properties including anticarcinogenic, antioxidant, antidiabetic, renoprotective, anti-atherosclerotic, antibacterial, antifungal, and antihypertensive activities in traditional medicines. A. sativum is rich in several sulfur-containing phytoconstituents such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids such as quercetin. Extracts and isolated compounds of A. sativum have been evaluated for various biological activities...
Károly Balog - Is there a cure for sepsis?
Author: by Károly Balog Literature title: Is there a cure for sepsis?
C1 Andrographis paniculata Extract (HMPL-004) for Active Ulcerative Colitis
Andrographis paniculata has in vitro inhibitory activity against TNF-a, IL-1p and NF-KB. A pilot study of A. paniculata extract (HMPL-004) suggested similar ef.cacy to mesalamine for ulcerative colitis. A randomized, double-blind, placebo-controlled trial evaluated the ef.cacy of A. paniculata extract (HMPL-004) in 224 adults with mild-to-moderate ulcerative colitis. Patients were randomized to A. paniculata extract (HMPL-004) 1,200 mg or 1,800 mg daily or placebo for 8 weeks. In total, 45 and 60 % of patients receiving A. paniculata 1,200 mg and 1,800 mg daily, respectively, were in clinical response at week 8, compared with 40 % of those who received...
C16 - Review on liver inflammation and anti-inflammatory activity of Andrographis paniculata for hepatoprotection
Till to date, the advancement of medical science and technology is still unable to provide inclusive treatment to liver inflammation caused by neither microbial invasion nor antibiotics nor environmental toxins. Therefore, this article provides the basic knowledge of liver inflammation up to the cellular level and its current medical treatment for inflammatory symptom suppression. Because of the adverse effects of drug treatment, people start looking for comprehensive alternative nowadays. Herbal medicine is believed to be the best of choice because it is being practiced until now for centuries. Although numerous herbal plants have been reported for their efficacies in liver...
C6 - Broad-spectrum antiviral properties of andrographolide
Broad-spectrum antiviral properties of andrographolide Download - PDF ABSTRACT Andrographolide, a diterpenoid, is known for its anti-inflammatory effects. It can be isolated from various plants of the genus Andrographis, commonly known as 'creat'. This purified compound has been tested for its anti-inflammatory effects in various stressful conditions, such as ischemia, pyrogenesis, arthritis, hepatic or neural toxicity, carcinoma, and oxidative stress, Apart from its anti-inflammatory effects, andrographolide also exhibits immunomodulatory effects by effectively enhancing cytotoxic T cells, natural killer (NK) cells, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC). All these properties of andrographolide form the foundation for the use of this miraculous
C7 - Fah Talai Jone proven effective in improving condition of COVID- 19 patients - DTAM
Extracts from the Fah Talai Jone (Andrographis Paniculata) medicinal plant have proven effective in improving the condition of those infected with COVID-19, after the traditional medicine was administered during clinical trials, jointly conducted by the Faculty of Medicine of Siriraj hospital, the Chulabhorn Research Institute, the Medical Science Department, the Government Pharmaceutical Organization and the Department of Thai Traditional and Alternative Medicine (DTAM). Source: https://www.thaipbsworld.com/fah-talai-jone-proven-effective-in-improving-condition-of-covid-19-patients-dtam/
C8 - Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond
Andrographis paniculata Wall (family Acanthaceae) is one of the most popular medicinal plants used traditionally for the treatment of array of diseases such as cancer, diabetes, high blood pressure, ulcer, leprosy, bronchitis, skin diseases, flatulence, colic, influenza, dysentery, dyspepsia and malaria for centuries in Asia, America and Africa continents. It possesses several photochemical constituents with unique and interesting biological properties. This review describes the past and present state of research on Andrographis paniculata with respect to the medicinal usage, phytochemistry, pharmacological activities, toxicity profile and therapeutic usage, in order to bridge the gap requiring future research opportunities. This review is...
C9 - Randomised clinical trial: herbal extract HMPL-004 in active ulcerative colitis - a double-blind comparison with sustained release mesalazine
Andrographis paniculatais an herbal mixture used to treat inflammatory diseases.An extract of the herb, HMPL-004, inhibits TNF-aand IL-1b,andprevents colitis in animal models. To determine the efficacy and safety of HMPL-004 in patients with mildto-moderate ulcerative colitis. A randomised, double-blind, multicentre, 8-week parallel group study was conducted using HMPL-004 1200 mg ⁄ day compared with 4500 mg ⁄ day of slow release mesalazine (mesalamine) granules in patients with mild-tomoderately active ulcerative colitis. Disease activity was assessed at baseline and every 2 weeks for clinical response, and at baseline and 8 weeks by colonoscopy. One hundred and twenty patients at five centres...
D3 - Marrubium vulgare L.: A Phytochemical and Pharmacological Overview
Marrubium vulgare is a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies, M. vulgare acts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+bacteria, fungi, herpes simplex virus, and parasites such as Toxoplasma gondii, Trichomonas vaginalis, and Plasmodium berghei-berghei was recorded. Additionally, it...
D5 - Evaluation of In Vitro Antioxidant and In Vivo Anti-inflammatory Potential of White Horehound (Marrubium vulgare L) Leaves
The present study was designed to explore the anti-inflammatory effect and antioxidant potential of the methanolic extract of Marrubium vulgare leaves, a popular traditional medicinal herb. In vivo anti-inflammatory activity was evaluated by the paw edema assay induced by carrageenin in rat model, while antioxidant activity was evaluated by two tests: assay of free radical-scavenging activity on DPPH and Ferric reducing antioxidant plasma (FRAP). Total phenolic and total flavonoid contents of the crude methanolic extract were also determined by Folin-Ciocalteu's phenol reagent and by aluminium chloride method, respectively. The results showed that methanol extract had high level of polyphenols (195...
D6 - A methanolic extract of Marrubium vulgareL. suppresses inflammatory responses in isoproterenol induced myocardial infarction in rat
Marrubium vulgare (Lamiaceae) is a medicinal herb and have been shown to have strong anti-inflammatory activities. The aim of the present study was to investigate the cardio protective effects of the methanolic extract of the plant on isoproterenol-induced acute myocardial infarction (MI). It is well known that inflammation plays a key role in the development of cardiovascular diseases. The results of our study demonstrated that a methanolic extract of Marrubium vulgare has strong protective effects against isoproterenol-induced myocardial infarction and this protection possibly is mediated through its anti-inflammatory actions. Source:http://www.rps.mui.ac.ir/index.php/jrps/article/view/977/961
E1 - Curcuma longa L. ameliorates asthma control in children and adolescents: a randomized, double-blind, controlled trial
Roots of Curcuma longa L. are used as medicine for millennia. They possess several pharmacological properties, including anti-inflammatory action, and can be suitable for asthma treatment. We aimed to test the hypothesis that, in children and adolescents with persistent asthma, the administration of powdered roots of C. longa for 6 months, in addition to standard treatment, compared to placebo, will result in better disease control. Patients and methods: We conducted a randomized, double-blind, placebo-controlled, phase II clinical trial. Patients were randomly assigned to receive 30 mg/kg/day of C. longa for 6 months, or placebo. Data were collected prospectively. All patients...
E11 - Efficacy of Curcumin as Adjuvant Therapy to Induce or Maintain Remission in Ulcerative Colitis Patients: an Evidence-based Clinical Review
Treatment guidelines for ulcerative colitis (UC) not yet established. Currently, mesalazine, corticosteroids, and immunomodulators are treatment options for UC. However, they are known to have unpleasant side effects such as nausea, vomiting, headaches, hepatitis, and male infertility. Curcumin is found in Turmeric plants (Curcuma longa L.), which possesses both anti-inflammatory and antioxidant properties. This study aimed to determine whether curcumin as adjuvant therapy can induce or maintain remission in UC patients. Structured search in three databases (Cochrane, PubMed, Proquest) using "curcumin", "remission" and "Ulcerative Colitis" as keywords. Inclusion criteria is randomized controlled trials (RCTs), meta-analysis, or systematic review using curcumin...
E12 - Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials Download - PDF Abstract Although turmeric and its curcumin-enriched extracts have been used for treating arthritis, no systematic review and meta-analysis of randomized clinical trials (RCTs) have been conducted to evaluate the strength of the research. We systemically evaluated all RCTs of turmeric extracts and curcumin for treating arthritis symptoms to elucidate the efficacy of curcuma for alleviating the symptoms of arthritis. Literature searches were conducted using 12 electronic databases, including PubMed, Embase, Cochrane Library, Korean databases, Chinese
E19 - Oral bioavailability of curcumin: problems and advancements
Curcumin is a natural compound of Curcuma longa L. and has shown many pharmacological activities such as anti-inflammatory, anti-oxidant in both preclinical and clinical studies. Moreover, curcumin has hepatoprotective, neuroprotective activities and protects against myocardial infarction. Particularly, curcumin has also demonstrated favorite anticancer efficacy. But limiting factors such as its extremely low oral bioavailability hampers its application as therapeutic agent. Therefore, many technologies have been developed and applied to overcome this limitation. This review described the main physicochemical properties of curcumin and summarized the recent studies in the design and development of oral delivery systems for curcumin to enhance the...
E21 - Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type1/type2 helper T-cells (Th1/Th2) balance in a mouse model of food allergy
Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type1/type2 helper T-cells (Th1/Th2) balance in a mouse model of food allergy Turmeric (Curcuma longa) has traditionally been used to treat pain, fever, allergic and inflammatory diseases such as bronchitis, arthritis, and dermatitis. In particular, turmeric and its active component, curcumin, were effective in ameliorating immune disorders including allergies. However, the effects of turmeric and curcumin have not yet been tested on food allergies. Mice were immunized with intraperitoneal ovalbumin (OVA) and alum. The mice were orally challenged with 50mg OVA, and treated with turmeric extract (100mg/kg), curcumin (3mg/kg or 30...
E4 - Curcuma longa L. ameliorates asthma control in children and adolescents
Curcuma longa L. ameliorates asthma control in children and adolescents: A randomized, double-blind, controlled trial Roots of Curcuma longa L. are used as medicine for millennia. They possess several pharmacological properties, including anti-inflammatory action, and can be suitable for asthma treatment. We aimed to test the hypothesis that, in children and adolescents with persistent asthma, the administration of powdered roots of C. longa for 6 months, in addition to standard treatment, compared to placebo, will result in better disease control. We conducted a randomized, double-blind, placebo-controlled, phase II clinical trial. Patients were randomly assigned to receive 30 mg/kg/day of C. longa for 6 months, in addition to standard treatment, compared to placebo.
E7 - Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kB inhibition
Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kB inhibition Curcumin, a polyphenol compound from Curcuma longa L. has been used for centuries as an anti-inflammatory remedy including asthma. Curcumin has been reported to exert an anti-inflammatory effect, in part, through inhibition of the NF-kB pathway. The purposes of this study were to determine whether curcumin inhibits NF-kB dependent transcription in vitro, and test whether treatment with curcumin reduces allergen-induced airway inflammation and hyper-responsiveness in a mouse model of asthma through inhibition of NF-kB pathway. The effect of curcumin on NF-kB transcriptional activity was investigated using a cell-based...
E8 - Curcumin (a constituent of turmeric): New treatment option against COVID-19
In late December 2019, the outbreak of respiratory illness emerged in Wuhan, China, and spreads worldwide. World Health Organization (WHO) named this disease severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused by a new member of beta coronaviruses. Several medications are prescribed to patients, and some clinical trials are underway. Scientists are trying to find a specific drug against this virus. In this review, we summarize the pathogenesis, clinical features, and current treatments of coronavirus disease 2019 (COVID-19). Then, we describe the possible therapeutic effects of curcumin and its molecular mechanism against coronavirus-19. Curcumin, as an active constituent of Curcuma...
F33 - Bile acid metabolism and signalling
Bile acids are important physiological agents for intestinal nutrient absorption and biliary secretion of lipids, toxic metabolites, and xenobiotics. Bile acids are also signaling molecules and metabolic regulators that activate nuclear receptors and G protein-coupled receptor (GPCR) signaling to regulate hepatic lipid, glucose, and energy homeostasis and maintain metabolic homeostasis. Conversion of cholesterol to bile acids is critical for maintaining cholesterol homeostasis and preventing accumulation of cholesterol, triglycerides, and toxic metabolites, and injury in the liver and other organs. Enterohepatic circulation of bile acids from the liver to intestine and back to the liver plays a central role in nutrient...
Reduces the effect of inflammation/viruses/bacteria/fungi through the antiseptic effect of bile - video
Short interview with Dr István Tihanyi, physician, iridologist, paediatrician, naturopath and László Béky, naturopath Source: Echo TV - Vitality programme 2015.05.13.
Direct or indirect effect of bile acids: Diarrhoea - Relief of constipation
Direct or indirect effect of bile acids: Helps to relieve herpes
Direct or indirect action of bile acids: Involved in the relief of sinusitis, sinusitis, pharyngitis and laryngitis
Direct or indirect action of bile acids: Interacts to alleviate the effects of dandruff, eczema
Physiological effects of the AntiBac ingredients: bile acids, elderberry, turmeric, white horehound, king of bitter, garlic
An expert discussion on the composition of AntiBac capsules and their physiological effects, which include: black elderberry supports the immune system to protect the human body. Garlic helps to maintain the microbiological balance of the gut and to defend against harmful bacteria and microorganisms. Bitter andrographis helps the body's natural defences, particularly at the level of the upper respiratory tract. Medicinal orchid helps the intestinal tract, contributing to healthy digestion and the normal functioning of the liver and bile. Turmeric + Black Pepper supports the immune system, lung and respiratory tract health and protection against allergies, it is a powerful antioxidant. More information in the video! Source: D1 Tv -...
B16 - Preventing the Common Cold With a Garlic Supplement
One hundred forty-six volunteers were randomised to receive a placebo or an allicin-containing garlic supplement, one capsule daily, over a 12-week period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. The active-treatment group had significantly fewer colds than the placebo group (24 vs 65, P<.001). The placebo group, in contrast, recorded significantly more days challenged virally (366 vs 111, P<.005) and a significantly longer duration of symptoms (5.01 vs 1.52 days, P<.001). Consequently, volunteers in the active group were less likely to get...
B21, C10 - COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?
COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy? Download - PDF Introduction The outbreak of coronavirus SARS-Cov-2 disease (COVID-19) in Wuhan (China) in late 2019 and its worldwide spread has caused hundreds of thousands of deaths so far. As of July 2020, the disease seems to be mostly affecting Europe and the Americas. Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. Older people and those with underlying medical problems such as cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to recover.
C12 - A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection
A randomized, double blind placebo controlled clinical study was conducted to evaluate the efficacy of KalmCold™, an extract of Andrographis paniculata, in patients with uncomplicated upper respiratory tract infection (URTI). The assessment involved quantification of symptom scores by Visual Analogue Scale. Nine self-evaluated symptoms of cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance were scored. A total of 223 patients of both sexes were randomized in two groups which received either KalmCold™ (200 mg/day) or placebo in a double blind manner. In both the treatments, mean scores of all symptoms showed a decreasing trend...
C13 - A randomized, controlled study of Kan Jang versus amantadine in the treatment of influenza in Volgograd
Two randomized, parallel-group clinical studies with a verum and a control group were performed to investigate the effect of a standardized extract (SHA-10) of Andrographis panaiculata (N.) fixed combination Kan Jang in the treatment of diagnosed influenza viral infection. The pilot study was performed on 540 patients with 71 Kan Jang-treated patients with the second phase conducted enrolling 66 patients. The differences in the duration of sick leave and frequency of post-influenza complications indicate that the Kan Jang phytopreparation not only contributes to faster recovery, but also reduces the risk of post-influenza complications. Kan Jang was well tolerated by patients....
C17 - Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children
Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children: a systematic review and meta-analysis Download - PDF Abstract Introduction: Antimicrobial resistance (AMR) is a substantial threat to public health. Safe and effective alternatives are required to reduce unnecessary antibiotic prescribing. Andrographis Paniculata (A. Paniculata, Chuān Xīn LiaÂn) has traditionally been used in Indian and Chinese herbal medicine for cough, cold and influenza, suggesting a role in respiratory tract infections (RTIs). This systematic review aimed to evaluate the clinical effectiveness and safety of A. Paniculata for symptoms of acute RTIs (ARTIs). Results: Thirty-three
E1 - Curcuma longa L. ameliorates asthma control in children and adolescents: a randomized, double-blind, controlled trial
Roots of Curcuma longa L. are used as medicine for millennia. They possess several pharmacological properties, including anti-inflammatory action, and can be suitable for asthma treatment. We aimed to test the hypothesis that, in children and adolescents with persistent asthma, the administration of powdered roots of C. longa for 6 months, in addition to standard treatment, compared to placebo, will result in better disease control. Patients and methods: We conducted a randomized, double-blind, placebo-controlled, phase II clinical trial. Patients were randomly assigned to receive 30 mg/kg/day of C. longa for 6 months, or placebo. Data were collected prospectively. All patients...
E4 - Curcuma longa L. ameliorates asthma control in children and adolescents
Curcuma longa L. ameliorates asthma control in children and adolescents: A randomized, double-blind, controlled trial Roots of Curcuma longa L. are used as medicine for millennia. They possess several pharmacological properties, including anti-inflammatory action, and can be suitable for asthma treatment. We aimed to test the hypothesis that, in children and adolescents with persistent asthma, the administration of powdered roots of C. longa for 6 months, in addition to standard treatment, compared to placebo, will result in better disease control. We conducted a randomized, double-blind, placebo-controlled, phase II clinical trial. Patients were randomly assigned to receive 30 mg/kg/day of C. longa for 6 months, in addition to standard treatment, compared to placebo.
E7 - Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kB inhibition
Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kB inhibition Curcumin, a polyphenol compound from Curcuma longa L. has been used for centuries as an anti-inflammatory remedy including asthma. Curcumin has been reported to exert an anti-inflammatory effect, in part, through inhibition of the NF-kB pathway. The purposes of this study were to determine whether curcumin inhibits NF-kB dependent transcription in vitro, and test whether treatment with curcumin reduces allergen-induced airway inflammation and hyper-responsiveness in a mouse model of asthma through inhibition of NF-kB pathway. The effect of curcumin on NF-kB transcriptional activity was investigated using a cell-based...
B10 - Garlic consumption and colorectal cancer risk in man: a systematic review and meta-analysis
Colorectal cancer shows large incidence variations worldwide that have been attributed to different dietary factors. We conducted a meta-analysis on the relationship between garlic consumption and colorectal cancer risk. We systematically reviewed publications obtained by searching ISI Web of Knowledge, MEDLINE and EMBASE literature databases. We extracted the risk estimate of the highest and the lowest reported categories of intake from each study and conducted meta-analysis using a random-effects model. The pooled analysis of all fourteen studies, seven cohort and seven case-control, indicated that garlic consumption was not associated with colorectal cancer risk (OR = 0-93; 95 % CI...
B13 - The association of garlic with Helicobacter pylori infection and gastric cancer risk
Background Garlic may be protective against Helicobacter pylori infection and gastric cancer development. We conducted this study to quantitatively update evidence on garlic intake and gastric cancer with the inclusion of most recent cohort studies and qualitatively summarize epidemiological studies of garlic consumption and Helicobacter pylori infection. Materials and methods PubMed, Embase, MEDLINE, and Cochrane Library were searched on April 2018. We conducted a meta-analysis to determine whether garlic intake reduced gastric cancer risk using random-effect models and a systematic review to summarize evidence on the association between garlic consumption and Helicobacter pylori infection. Risk of bias was assessed using...
B16 - Preventing the Common Cold With a Garlic Supplement
One hundred forty-six volunteers were randomised to receive a placebo or an allicin-containing garlic supplement, one capsule daily, over a 12-week period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. The active-treatment group had significantly fewer colds than the placebo group (24 vs 65, P<.001). The placebo group, in contrast, recorded significantly more days challenged virally (366 vs 111, P<.005) and a significantly longer duration of symptoms (5.01 vs 1.52 days, P<.001). Consequently, volunteers in the active group were less likely to get...
B19. allicin as add-on therapy for Helicobacter pylori infection: a systematic review and meta-analysis
Allicin (2-propene-1-sulfinothioic acid S-2-propenyl ester, diallyl thiosulfinate) extracted from garlic, has proven activity against Helicobacter pylori (H. pylori) infection. In recent years, clinical trials have explored its utility as an add-on therapy with variable outcomes reported. To perform a systemic review of allicin as an add-on treatment for H. pylori infection and assess its efficacy in randomized controlled trials (RCTs). Electronic databases including MEDLINE, EMBASE, the Web of Science, the Cochrane Database, the China National Knowledge Infrastructure Database, Chinese VIP Information Databases, Chinese Medical Databases, and the Wan-Fang Database were searched for keywords including "allicin", "Helicobacter pylori", "randomized clinical trials",...
B2 - Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data
Garlic (Allium sativum L.) is a common herb consumed worldwide as functional food and traditional remedy for the prevention of infectious diseases since ancient time. Garlic and its active organosulfur compounds (OSCs) have been reported to alleviate a number of viral infections in pre-clinical and clinical investigations. However, so far no systematic review on its antiviral effects and the underlying molecular mechanisms exists. The aim of this review is to systematically summarize pre-clinical and clinical investigations on antiviral effects of garlic and its OSCs as well as to further analyse recent findings on the mechanisms that underpin these antiviral actions....
C2 Andrographis paniculata (Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry, and Pharmacology
The demand of AP is greatly increased in the past few years for its overwhelming therapeutic potentials. Available data on AP also clearly expresses a broad spectrum of pharmacological properties of this plant. Due to possessing extensive pharmacological activities, the AP can be safely regarded as one of the modern catholicons. However, the investigated pharmacological activities of AP need validation through the clinical study. Though several clinical studies were successfully completed without adverse effects or fatalities, most of them only investigated upper respiratory tract infections for a variety of conditions. Verification of the efficacy of other biological activities of AP...
C8 - Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond
Andrographis paniculata Wall (family Acanthaceae) is one of the most popular medicinal plants used traditionally for the treatment of array of diseases such as cancer, diabetes, high blood pressure, ulcer, leprosy, bronchitis, skin diseases, flatulence, colic, influenza, dysentery, dyspepsia and malaria for centuries in Asia, America and Africa continents. It possesses several photochemical constituents with unique and interesting biological properties. This review describes the past and present state of research on Andrographis paniculata with respect to the medicinal usage, phytochemistry, pharmacological activities, toxicity profile and therapeutic usage, in order to bridge the gap requiring future research opportunities. This review is...
D2 - Phytochemical screening and antiviral activity of Marrubium vulgare
Introduction Aims: The present study is to investigate the phytochemical content, cytotoxicity and antiviral activity of the crude and fractions from Marrubium vulgare. Methodology and results: The crude methanol extract and fractions using hexane, chloroform, ethyl acetate and n-butanol of M. vulgare whole plant were produced in this study. Qualitative phytochemical analysis revealed the presence of flavones aglycones and steroid in all preparations except for the hexane fraction. Carbohydrates, saponins were found present in the crude and ethyl acetate extracts while tannin was detected in the crude, ethyl acetate and butanol extracts. Anthraquinones and terpenes were detected in the hexane...
D3 - Marrubium vulgare L.: A Phytochemical and Pharmacological Overview
Marrubium vulgare is a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies, M. vulgare acts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+bacteria, fungi, herpes simplex virus, and parasites such as Toxoplasma gondii, Trichomonas vaginalis, and Plasmodium berghei-berghei was recorded. Additionally, it...
D4 - Chemical Characterization and Antibacterial Activity of Phases Obtained from Extracts of Artemisia herba alba, Marrubium vulgare and Pinus pinaster
Chemical Characterization and Antibacterial Activity of Phases Obtained from Extracts of Artemisia herba alba, Marrubium vulgare and Pinus pinaster Download - PDF Abstract The objective of this study is the phytochemical characterization and antibacterial activity of Artemisia herba alba, Marrubium vulgare and Pinus pinaster. The antibacterial potential of different fractions of ethyl acetate, diethyl ether and 1 butanol extracts of the three plants were tested on four strains of bacteria: Staphylococcus aureus, Escherichia coli, Proteus vulgaris and Pseudomonas aeruginosa. The results of phytochemical screening showed a rich and varied composition of secondary metabolites: flavonoids, tannins, terpenes, sterols, coumarins and saponins
E21 - Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type1/type2 helper T-cells (Th1/Th2) balance in a mouse model of food allergy
Turmeric (Curcuma longa) attenuates food allergy symptoms by regulating type1/type2 helper T-cells (Th1/Th2) balance in a mouse model of food allergy Turmeric (Curcuma longa) has traditionally been used to treat pain, fever, allergic and inflammatory diseases such as bronchitis, arthritis, and dermatitis. In particular, turmeric and its active component, curcumin, were effective in ameliorating immune disorders including allergies. However, the effects of turmeric and curcumin have not yet been tested on food allergies. Mice were immunized with intraperitoneal ovalbumin (OVA) and alum. The mice were orally challenged with 50mg OVA, and treated with turmeric extract (100mg/kg), curcumin (3mg/kg or 30...
G16 - Physiological effects of endotoxin
The physiological role of endotoxin in humans is multifaceted and dose-dependent. We now know that endotoxins only exert their effects when released from the surface of Gram-negative bacteria. This can happen when the bacterium dies or when it starts to multiply. Normally, millions of Gram-negative bacteria live in the mammalian body and do not cause any health problems. In pathological cases, endotoxemia occurs as a result of large amounts of endotoxin entering the bloodstream, which can cause trauma and shock. Endotoxins act mainly through macrophages. These cells, which play a protective role, normally absorb and break down substances harmful to the body. Live or dead bacteria...
G17 - Gram negative sepsis and shock
In the modern hospital gram negative bacteremia and the associated condition of septic shock are common occurrences. In the United States the estimated incidence of gram negative bacteremia ranges from 71,000 to 330,000 cases annually. Fatalities attributed to this disease are between 18,000 and 132,000 each year. Sepsis is defined as a systemic disease caused by microorganisms or their products in the blood. Bacteremia is the presence of viable organisms in the circulation. Gram negative bacteremia in the critically ill patient is synonymous with gram negative sepsis. Septic shock is a clinical syndrome characterized by circulatory insufficiency and inadequate tissue...
G18 - Changes in the prevalence of multi-drug resistant pathogens and implications for the ICU
Incidence of nosocomial infections and antibiotic resistance in intensive care units is increasing worldwide. Blood-stream infections of Gram-negative non-fermentative bacteria are associated with higher mortality. The aim of this study was to compare the antibiotic sensitivity of nosocomial blood-stream infections between years 2008-2010. There was no difference in the sensitivity of methycillin-resistant Staphylococcus aureus and extended-spectrum beta lactamase producing Klebsiella spp. and Escherichia coli infections between the two years examined. Antibiotic resistance of Acinetobacter baumannii and Pseudomonas infections showed a marked increase in 2010 when compared to that found in 2008: there was no multiresistant Acinetobacter infection in samples obtained...
Direct or indirect action of bile acids: Helps relieve chronic pancreatitis
The seven ingredients of AntiBac relieve the symptoms of colds, flus and flu both individually and synergistically!
'A cold, or cold, or rhinitis, is a viral infection of the upper respiratory tract that primarily attacks the mucous membranes of the nose and throat, but can also appear in the lungs. There is no precise scientific or medical definition of a cold (the only thing to do with colds is that pathogens are seasonally more active in winter). The most common pathogen is rhinovirus, but it can be caused by more than 200 different viruses and sometimes bacterial infection can aggravate symptoms. Colds are often mistaken for the much more serious flu. Colds are the most common type of infection in humans. Symptoms include cough, sore throat, runny nose and fever, depending on severity and extent. A...
A3 - Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses
Black elderberries (Sambucus nigra L.) are well known as supportive agents against common cold and influenza. It is further known that bacterial super-infection during an influenza virus (IV) infection can lead to severe pneumonia. We have analyzed a standardized elderberry extract (Rubini, BerryPharma AG) for its antimicrobial and antiviral activity using the microtitre broth micro-dilution assay against three Gram-positive bacteria and one Gram-negative bacteria responsible for infections of the upper respiratory tract, as well as cell culture experiments for two different strains of influenza virus. The antimicrobial activity of the elderberry extract was determined by bacterial growth experiments in liquid...
A6 - Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama
Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama Download - PDF Abstract A standardized elderberry extract, Sambucol® (SAM), reduced hemagglutination and inhibited replication of human influenza viruses type A/Shangdong 9/93 (H3N2), A/Beijing 32/92 (H3N2), A/Texas 36/91 (HlNl), A/Singapore 6/86 (HlNl), type B/Panama 45/90, B/Yamagata 16/88, B/Ann Arbor 1/86, and of animal strains from Northern European swine and turkeys, A/Sw/Ger 2/81, A/Tur/Ger 3/91, and A/Sw/Ger 8533/91 in Madin-Darby canine kidney cells. A placebo-controlled, double blind study was carried out on a group
AntiBac capsules in brief: boosting immunity, alleviating side effects and complications of infections - video
Short presentation of Dr. Antal Miklós Várhalmi, developer of AntiBac food supplements at the WFC Hungary Conference 2021.05.08.
Physiological effects of the AntiBac ingredients: bile acids, elderberry, turmeric, white horehound, king of bitter, garlic
An expert discussion on the composition of AntiBac capsules and their physiological effects, which include: black elderberry supports the immune system to protect the human body. Garlic helps to maintain the microbiological balance of the gut and to defend against harmful bacteria and microorganisms. Bitter andrographis helps the body's natural defences, particularly at the level of the upper respiratory tract. Medicinal orchid helps the intestinal tract, contributing to healthy digestion and the normal functioning of the liver and bile. Turmeric + Black Pepper supports the immune system, lung and respiratory tract health and protection against allergies, it is a powerful antioxidant. More information in the video! Source: D1 Tv -...
The role of digestion and bile function in the proper functioning of the immune system and in the defence against infections
Source: Zöld Újság December 2021 In the stomach, hydrochloric acid helps to neutralise and break down many bacteria, viruses, fungi and micro-organisms, which is a great help for our immune system, but we can also help to protect our health by paying attention to the proper cycle of bile acids of our body. In the lower intestinal tract, bile and bile acids also have an antiseptic effect, and if there is not enough bile produced, these antiseptic functions will not work properly. In the current infection season, we can support our immune system not only by absorbing the food we eat and getting enough vitamins into our bodies. Most of the arrowheads are located in the intestinal wall and around the intestinal tract, which have the...
What can be done to relieve the symptoms of various infections and help them to go away more quickly?
Infection means the harmful colonisation of a host by pathogens. In infection, the infecting organism seeks to use the resources of the host to reproduce. The infecting organism may also cause abnormal function and possibly destroy the host. The most common symptoms of bacterial and viral infections are: fever, limb and joint pain, runny nose, nasal congestion, sore throat, cough, sneezing, headache, weakness, lethargy, chills, digestive problems (constipation or diarrhoea), rashes and other skin problems, etc. In addition to consulting a doctor and following his/her advice, the most important things to do are: relieving fever, cough, nasal congestion, pain relief, drinking plenty of fluids, eating right, taking vitamins and minerals, trace elements, etc.
Newsletter 9: Autumn is here, and it's that time again... for respiratory infections
🦠 If you or someone you care about is experiencing symptoms similar to a cold, the most important things to do are to see a doctor and follow his or her advice: stop fever, stop coughing, relieve pain, eat right, drink plenty of fluids, etc. (and we're not talking about a hat cure). In addition to the above, vitamins C and D, herbs known from folk medicine and scientific research are also effective in alleviating the symptoms of various bacterial and viral infections and colds, and in speeding up their progress, the most important of which are also included in AntiBac 💊. 🧄 Garlic: one capsule of GALLMET-Immun (AntiBac) contains the active ingredient of several cloves of garlic, which inhibits the multiplication of many respiratory pathogens (bacteria, viruses)
The seven ingredients of AntiBac relieve the symptoms of colds, flus and flu both individually and synergistically!
'A cold, or cold, or rhinitis, is a viral infection of the upper respiratory tract that primarily attacks the mucous membranes of the nose and throat, but can also appear in the lungs. There is no precise scientific or medical definition of a cold (the only thing to do with colds is that pathogens are seasonally more active in winter). The most common pathogen is rhinovirus, but it can be caused by more than 200 different viruses and sometimes bacterial infection can aggravate symptoms. Colds are often mistaken for the much more serious flu. Colds are the most common type of infection in humans. Symptoms include cough, sore throat, runny nose and fever, depending on severity and extent. A...
A1 - Antiviral properties of Elderberry
Sambucus nigra products (Sambucol) have antiviral properties against different strains of influenza virus. Sambucol Elderberry Extract and its formulations activate the healthy immune system by increasing inflammatory cytokine production. Standardized elderberry liquid extract possesses antimicrobial activity against both Gram-positive bacteria of Streptococcus pyogenes and group C and G Streptococci, and the Gram-negative bacterium Branhamella catarrhalis in liquid cultures. Sambucus Formosana Nakai stem ethanol extract displayed the strong anti-HCoV-NL63 (human coronavirus NL63) potential. Source:https://www.researchgate.net/publication/340236781_Antiviral_properties_of_Elderberry
A3 - Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses
Black elderberries (Sambucus nigra L.) are well known as supportive agents against common cold and influenza. It is further known that bacterial super-infection during an influenza virus (IV) infection can lead to severe pneumonia. We have analyzed a standardized elderberry extract (Rubini, BerryPharma AG) for its antimicrobial and antiviral activity using the microtitre broth micro-dilution assay against three Gram-positive bacteria and one Gram-negative bacteria responsible for infections of the upper respiratory tract, as well as cell culture experiments for two different strains of influenza virus. The antimicrobial activity of the elderberry extract was determined by bacterial growth experiments in liquid...
A4 - Randomized Study of the Efficacy and Safety of Oral Elderberry Extract in the Treatment of Influenza A and B Virus Infections
Randomized Study of the Efficacy and Safety of Oral Elderberry Extract in the Treatment of Influenza A and B Virus Infections Download - PDF Introduction The influenza virus is an orthomyxovirus and causes an acute respiratory tract disease. Influenza is typically characterized by abrupt onset of fever, headache, myalgia, sore throat and non-productive cough. The illness is usually self-limiting, with relief of symptoms occurring within 5 - 7 days. Nevertheless, it is an important disease due to its ease of communicability, short incubation time, rapid rate of viral mutation, related morbidity, resultant loss of productivity, and the possibility of severe
A5 - Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers
Intercontinental air travel can be stressful, especially for respiratory health. Elderberries have been used traditionally, and in some observational and clinical studies, as supportive agents against the common cold and influenza. This randomised, double-blind placebo-controlled clinical trial of 312 economy class passengers travelling from Australia to an overseas destination aimed to investigate if a standardised membrane filtered elderberry (Sambucus nigra L.) extract has beneficial effects on physical, especially respiratory, and mental health. Cold episodes, cold duration and symptoms were noted in a daily diary and assessed using the Jackson score. Participants also completed three surveys containing questions regarding upper respiratory...
A6 - Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama
Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama Download - PDF Abstract A standardized elderberry extract, Sambucol® (SAM), reduced hemagglutination and inhibited replication of human influenza viruses type A/Shangdong 9/93 (H3N2), A/Beijing 32/92 (H3N2), A/Texas 36/91 (HlNl), A/Singapore 6/86 (HlNl), type B/Panama 45/90, B/Yamagata 16/88, B/Ann Arbor 1/86, and of animal strains from Northern European swine and turkeys, A/Sw/Ger 2/81, A/Tur/Ger 3/91, and A/Sw/Ger 8533/91 in Madin-Darby canine kidney cells. A placebo-controlled, double blind study was carried out on a group
A7 - Sambucus nigra extracts inhibit infectious bronchitis virus at an early point during replication
Background: Infectious bronchitis virus (IBV) is a pathogenic chicken coronavirus. Currently, vaccination against IBV is only partially protective; therefore, better preventions and treatments are needed. Plants produce antimicrobial secondary compounds, which may be a source for novel anti-viral drugs. Non-cytotoxic, crude ethanol extracts of Rhodiola rosea roots, Nigella sativa seeds, and Sambucus nigra fruit were tested for anti-IBV activity, since these safe, widely used plant tissues contain polyphenol derivatives that inhibit other viruses. Results: Dose-response cytotoxicity curves on Vero cells using trypan blue staining determined the highest non-cytotoxic concentrations of each plant extract. To screen for IBV inhibition, cells and...
A9 - Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms
Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: a meta-analysis of randomized, controlled clinical trials Download - PDF Abstract Upper respiratory symptoms are often treated with over the counter drugs, antibiotics, and antiviral medications. Due to concerns about safety and efficacy, there is a demand for an alternative solution. Black elderberry (Sambucus nigra) has been used to treat cold and flu symptoms, but there are no large-scale studies or meta-analyses. This meta-analysis quantifies the effects of elderberry supplementation and evaluates moderators including vaccination status and the underlying pathology. This analysis included a total of 180 participants and evaluates
AntiBac capsules in brief: boosting immunity, alleviating side effects and complications of infections - video
Short presentation of Dr. Antal Miklós Várhalmi, developer of AntiBac food supplements at the WFC Hungary Conference 2021.05.08.
Physiological effects of the AntiBac ingredients: bile acids, elderberry, turmeric, white horehound, king of bitter, garlic
An expert discussion on the composition of AntiBac capsules and their physiological effects, which include: black elderberry supports the immune system to protect the human body. Garlic helps to maintain the microbiological balance of the gut and to defend against harmful bacteria and microorganisms. Bitter andrographis helps the body's natural defences, particularly at the level of the upper respiratory tract. Medicinal orchid helps the intestinal tract, contributing to healthy digestion and the normal functioning of the liver and bile. Turmeric + Black Pepper supports the immune system, lung and respiratory tract health and protection against allergies, it is a powerful antioxidant. More information in the video! Source: D1 Tv -...
The role of digestion and bile function in the proper functioning of the immune system and in the defence against infections
Source: Zöld Újság December 2021 In the stomach, hydrochloric acid helps to neutralise and break down many bacteria, viruses, fungi and micro-organisms, which is a great help for our immune system, but we can also help to protect our health by paying attention to the proper cycle of bile acids of our body. In the lower intestinal tract, bile and bile acids also have an antiseptic effect, and if there is not enough bile produced, these antiseptic functions will not work properly. In the current infection season, we can support our immune system not only by absorbing the food we eat and getting enough vitamins into our bodies. Most of the arrowheads are located in the intestinal wall and around the intestinal tract, which have the...
B16 - Preventing the Common Cold With a Garlic Supplement
One hundred forty-six volunteers were randomised to receive a placebo or an allicin-containing garlic supplement, one capsule daily, over a 12-week period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. The active-treatment group had significantly fewer colds than the placebo group (24 vs 65, P<.001). The placebo group, in contrast, recorded significantly more days challenged virally (366 vs 111, P<.005) and a significantly longer duration of symptoms (5.01 vs 1.52 days, P<.001). Consequently, volunteers in the active group were less likely to get...
B5 - Efficacy of Garlic and Onion against virus
In the current scenario, pharmaceutical industry is dependent on chemical based drugs to treat viral infection. However, these drugs are known to induce many side effects in human body. There is pressing need to promote safe alternative to chemical based antiviral drugs. Onion and garlic are natural sources which are known to possess antiviral properties. It is well known that onion and garlic are rich source of organosulfur compounds. Organosulfur compounds like quercetin and allicin are associated with inhibition of viral infection. These chemicals can hinder virus attachment to host cell, alter transcription and translation of viral genome in host...
B9 - Garlic Lowers Blood Pressure in Hypertensive Individuals, Regulates Serum Cholesterol, and Stimulates Immunity: An Updated Meta-analysis and Review
Garlic Lowers Blood Pressure in Hypertensive Individuals, Regulates Serum Cholesterol, and Stimulates Immunity: An Updated Meta-analysis and Review Garlic has been shown to have cardiovascular protective and immunomodulatory properties. We updated a previous meta-analysis on the effect of garlic on blood pressure and reviewed the effect of garlic on cholesterol and immunity. We searched the Medline database for randomized controlled trials (RCTs) published between 1955 and December 2013 on the effect of garlic preparations on blood pressure. In addition, we reviewed the effect of garlic on cholesterol and immunity. Our updated meta-analysis on the effect of garlic on blood pressure,...
C12 - A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection
A randomized, double blind placebo controlled clinical study was conducted to evaluate the efficacy of KalmCold™, an extract of Andrographis paniculata, in patients with uncomplicated upper respiratory tract infection (URTI). The assessment involved quantification of symptom scores by Visual Analogue Scale. Nine self-evaluated symptoms of cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance were scored. A total of 223 patients of both sexes were randomized in two groups which received either KalmCold™ (200 mg/day) or placebo in a double blind manner. In both the treatments, mean scores of all symptoms showed a decreasing trend...
C13 - A randomized, controlled study of Kan Jang versus amantadine in the treatment of influenza in Volgograd
Two randomized, parallel-group clinical studies with a verum and a control group were performed to investigate the effect of a standardized extract (SHA-10) of Andrographis panaiculata (N.) fixed combination Kan Jang in the treatment of diagnosed influenza viral infection. The pilot study was performed on 540 patients with 71 Kan Jang-treated patients with the second phase conducted enrolling 66 patients. The differences in the duration of sick leave and frequency of post-influenza complications indicate that the Kan Jang phytopreparation not only contributes to faster recovery, but also reduces the risk of post-influenza complications. Kan Jang was well tolerated by patients....
C17 - Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children
Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children: a systematic review and meta-analysis Download - PDF Abstract Introduction: Antimicrobial resistance (AMR) is a substantial threat to public health. Safe and effective alternatives are required to reduce unnecessary antibiotic prescribing. Andrographis Paniculata (A. Paniculata, Chuān Xīn LiaÂn) has traditionally been used in Indian and Chinese herbal medicine for cough, cold and influenza, suggesting a role in respiratory tract infections (RTIs). This systematic review aimed to evaluate the clinical effectiveness and safety of A. Paniculata for symptoms of acute RTIs (ARTIs). Results: Thirty-three
C2 Andrographis paniculata (Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry, and Pharmacology
The demand of AP is greatly increased in the past few years for its overwhelming therapeutic potentials. Available data on AP also clearly expresses a broad spectrum of pharmacological properties of this plant. Due to possessing extensive pharmacological activities, the AP can be safely regarded as one of the modern catholicons. However, the investigated pharmacological activities of AP need validation through the clinical study. Though several clinical studies were successfully completed without adverse effects or fatalities, most of them only investigated upper respiratory tract infections for a variety of conditions. Verification of the efficacy of other biological activities of AP...
C3 - Andrographolide and its fluorescent derivative inhibit the main proteases of 2019-nCoV and SARS-CoV through covalent linkage
Andrographolide and its fluorescent derivative inhibit the main proteases of 2019-nCoV and SARS-CoV through covalent linkage Download - PDF ABSTRACT: The coronavirus disease 2019 (COVID-19) pandemic caused by 2019 novel coronavirus (2019-nCoV) has been a crisis of global health, whereas the effective vaccines against 2019-nCoV are still under development. Alternatively, utilization of old drugs or available medicine that can suppress the viral activity or replication may provide an urgent solution to suppress the rapid spread of 2019-nCoV. Andrographolide is a highly abundant natural product of the medicinal plant, Andrographis paniculata, which has been clinically used for inflammatory diseases and anti-viral
C4 - Andrographolide as a potent and promising antiviral agent
Andrographolide as a potent and promising antiviral agent Download - PDF ABSTRACT Andrographolide is a labdane diterpenoid extracted and purified from the aerial parts of plants belonging to genus Andrographis (Acanthaceae). The research has shown the plant based compound is low cytotoxic, having antimicrobial, anti-cancer, antiviral and anti-parasitic effects. Andrographolide both prevent spread as well as transmission of virus to neighboring cells by interfering with different cell signaling pathways. In addition to its medicinal value, plant has been found having nutritional value. Therefore being cost effective, easy availability and having nutritional value as a natural supplement, can be used to
C7 - Fah Talai Jone proven effective in improving condition of COVID- 19 patients - DTAM
Extracts from the Fah Talai Jone (Andrographis Paniculata) medicinal plant have proven effective in improving the condition of those infected with COVID-19, after the traditional medicine was administered during clinical trials, jointly conducted by the Faculty of Medicine of Siriraj hospital, the Chulabhorn Research Institute, the Medical Science Department, the Government Pharmaceutical Organization and the Department of Thai Traditional and Alternative Medicine (DTAM). Source: https://www.thaipbsworld.com/fah-talai-jone-proven-effective-in-improving-condition-of-covid-19-patients-dtam/
D1 - An Insight into a Blockbuster Phytomedicine; Marrubium vulgare L. Herb. More of a Myth than a Reality?
Aerial parts and the root of Marrubium vulgare L. (white horehound) have been traditionally used in Europe and in southern and eastern Mediterranean countries. During colonization, the plant was introduced in America to great levels of popularity because of the simplicity of its growing; it was especially popular in Mexico and Brazil, where it has been known as 'maromba', 'marroio' or 'marroio-branco'. Ethnopharmacological uses of M. vulgare include treating respiratory diseases such as acute or chronic bronchitis, colds and asthma. The plant is also used in cases where there is a lack of appetite or dyspepsia and for diagnosed type...
E1 - Curcuma longa L. ameliorates asthma control in children and adolescents: a randomized, double-blind, controlled trial
Roots of Curcuma longa L. are used as medicine for millennia. They possess several pharmacological properties, including anti-inflammatory action, and can be suitable for asthma treatment. We aimed to test the hypothesis that, in children and adolescents with persistent asthma, the administration of powdered roots of C. longa for 6 months, in addition to standard treatment, compared to placebo, will result in better disease control. Patients and methods: We conducted a randomized, double-blind, placebo-controlled, phase II clinical trial. Patients were randomly assigned to receive 30 mg/kg/day of C. longa for 6 months, or placebo. Data were collected prospectively. All patients...
E2 - Immunomodulatory activity of curcumin
Curcumin, an active ingredient present in Curcuma longa, was analysed for the immunomodulatory activity in Balb/c mice. Curcumin administration was found to increase the total WBC count (15,290) significantly on the 12th day Group of animals treated with vehicle alone showed results similar to that of normal animals (10,130 on 12th day). Curcumin increased the circulating antibody titre (512) against SRBC. Curcumin administration increased the plague forming cells (PFC) in the spleen and the maximum number of RFC was observed on the 6th day (1,130 PFC/10® spleen cells) after immunization with SRBC. Bone marrow cellularity (16.9×10 cells/femur) and a. -esterase...
E6 - Curcumin Attenuates Allergen-Induced Airway Hyperresponsiveness in Sensitized Guinea Pigs
Curcumin Attenuates Allergen-Induced Airway Hyperresponsiveness in Sensitized Guinea Pigs Download - PDF ABSTRACT Anti-asthmatic property of curcumin (diferuloylmethane), a natural product from the rhizomes of Curcuma longa, has been tested in a guinea pig model of airway hyperresponsiveness. We sensitized guinea pigs with ovalbumin (OVA) to develop certain characteristic features of asthma: allergen-induced airway constriction and airway hyperreactivity to histamine. Guinea pigs were treated with curcumin during sensitization (to examine its preventive effect) or after developing impaired airways features (to examine its therapeutic effect). Status of airway constriction and airway hyperreactivity were determined by measuring specific airway conductance (SGaw)
E7 - Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kB inhibition
Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kB inhibition Curcumin, a polyphenol compound from Curcuma longa L. has been used for centuries as an anti-inflammatory remedy including asthma. Curcumin has been reported to exert an anti-inflammatory effect, in part, through inhibition of the NF-kB pathway. The purposes of this study were to determine whether curcumin inhibits NF-kB dependent transcription in vitro, and test whether treatment with curcumin reduces allergen-induced airway inflammation and hyper-responsiveness in a mouse model of asthma through inhibition of NF-kB pathway. The effect of curcumin on NF-kB transcriptional activity was investigated using a cell-based...
E8 - Curcumin (a constituent of turmeric): New treatment option against COVID-19
In late December 2019, the outbreak of respiratory illness emerged in Wuhan, China, and spreads worldwide. World Health Organization (WHO) named this disease severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused by a new member of beta coronaviruses. Several medications are prescribed to patients, and some clinical trials are underway. Scientists are trying to find a specific drug against this virus. In this review, we summarize the pathogenesis, clinical features, and current treatments of coronavirus disease 2019 (COVID-19). Then, we describe the possible therapeutic effects of curcumin and its molecular mechanism against coronavirus-19. Curcumin, as an active constituent of Curcuma...
Alleviating biliary diseases, viral infections, cardiovascular diseases with food supplements
Dr. Antal Miklós Várhalmi has been working with bile acids and the cycle of bile acids for 30 years. Due to personal involvement and with the aim of helping other people, he created a range of products containing natural bile acids about 10 years ago. GALLMET bile acid capsules have helped many people with digestive and other problems. Abnormalities in bile production and bile deficiency can affect our digestion and health. For more information: https://gallmet.hu/osszes-egeszsegugyi-javaslat/emesztes-es-epe-mukodes/ Then, because bile acids are also good for the immune system, he developed AntiBac. In addition to bile acids, it contains herbs (elderberries, garlic, turmeric, androgyrosis, black pepper) that help to alleviate the symptoms and side effects of various infections. More...
How can bile acids and herbs help with bacterial and viral infections?
Naturportal podcast 2022.08.31. Dr. Miklós Várhalmi has been working with bile acids and enterohepatic circuits for 30 years. Developer of bile acid related products. What are bile acids? What can they do for you? How do bile acids affect the immune system? How can bile acids help with viruses and bacteria? What can medical pemethrum, black elderberry, garlic, andrographis, turmeric, black pepper and complexene help with? What herb is andrographis? Can this complex help with covid and other viruses? What bacterial infections can it help with? Presenters.
What can be done to relieve the symptoms of various infections and help them to go away more quickly?
Infection means the harmful colonisation of a host by pathogens. In infection, the infecting organism seeks to use the resources of the host to reproduce. The infecting organism may also cause abnormal function and possibly destroy the host. The most common symptoms of bacterial and viral infections are: fever, limb and joint pain, runny nose, nasal congestion, sore throat, cough, sneezing, headache, weakness, lethargy, chills, digestive problems (constipation or diarrhoea), rashes and other skin problems, etc. In addition to consulting a doctor and following his/her advice, the most important things to do are: relieving fever, cough, nasal congestion, pain relief, drinking plenty of fluids, eating right, taking vitamins and minerals, trace elements, etc.
Direct or indirect effect of bile acids: Contributes to lowering cholesterol levels
A1 - Antiviral properties of Elderberry
Sambucus nigra products (Sambucol) have antiviral properties against different strains of influenza virus. Sambucol Elderberry Extract and its formulations activate the healthy immune system by increasing inflammatory cytokine production. Standardized elderberry liquid extract possesses antimicrobial activity against both Gram-positive bacteria of Streptococcus pyogenes and group C and G Streptococci, and the Gram-negative bacterium Branhamella catarrhalis in liquid cultures. Sambucus Formosana Nakai stem ethanol extract displayed the strong anti-HCoV-NL63 (human coronavirus NL63) potential. Source:https://www.researchgate.net/publication/340236781_Antiviral_properties_of_Elderberry
A3 - Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses
Black elderberries (Sambucus nigra L.) are well known as supportive agents against common cold and influenza. It is further known that bacterial super-infection during an influenza virus (IV) infection can lead to severe pneumonia. We have analyzed a standardized elderberry extract (Rubini, BerryPharma AG) for its antimicrobial and antiviral activity using the microtitre broth micro-dilution assay against three Gram-positive bacteria and one Gram-negative bacteria responsible for infections of the upper respiratory tract, as well as cell culture experiments for two different strains of influenza virus. The antimicrobial activity of the elderberry extract was determined by bacterial growth experiments in liquid...
A4 - Randomized Study of the Efficacy and Safety of Oral Elderberry Extract in the Treatment of Influenza A and B Virus Infections
Randomized Study of the Efficacy and Safety of Oral Elderberry Extract in the Treatment of Influenza A and B Virus Infections Download - PDF Introduction The influenza virus is an orthomyxovirus and causes an acute respiratory tract disease. Influenza is typically characterized by abrupt onset of fever, headache, myalgia, sore throat and non-productive cough. The illness is usually self-limiting, with relief of symptoms occurring within 5 - 7 days. Nevertheless, it is an important disease due to its ease of communicability, short incubation time, rapid rate of viral mutation, related morbidity, resultant loss of productivity, and the possibility of severe
A5 - Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers
Intercontinental air travel can be stressful, especially for respiratory health. Elderberries have been used traditionally, and in some observational and clinical studies, as supportive agents against the common cold and influenza. This randomised, double-blind placebo-controlled clinical trial of 312 economy class passengers travelling from Australia to an overseas destination aimed to investigate if a standardised membrane filtered elderberry (Sambucus nigra L.) extract has beneficial effects on physical, especially respiratory, and mental health. Cold episodes, cold duration and symptoms were noted in a daily diary and assessed using the Jackson score. Participants also completed three surveys containing questions regarding upper respiratory...
A6 - Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama
Inhibition of Several Strains of Influenza Virus in Vitro and Reduction of Symptoms by an Elderberry Extract (Sambucus nigra L.) during an Outbreak of Influenza B Panama Download - PDF Abstract A standardized elderberry extract, Sambucol® (SAM), reduced hemagglutination and inhibited replication of human influenza viruses type A/Shangdong 9/93 (H3N2), A/Beijing 32/92 (H3N2), A/Texas 36/91 (HlNl), A/Singapore 6/86 (HlNl), type B/Panama 45/90, B/Yamagata 16/88, B/Ann Arbor 1/86, and of animal strains from Northern European swine and turkeys, A/Sw/Ger 2/81, A/Tur/Ger 3/91, and A/Sw/Ger 8533/91 in Madin-Darby canine kidney cells. A placebo-controlled, double blind study was carried out on a group
A9 - Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms
Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: a meta-analysis of randomized, controlled clinical trials Download - PDF Abstract Upper respiratory symptoms are often treated with over the counter drugs, antibiotics, and antiviral medications. Due to concerns about safety and efficacy, there is a demand for an alternative solution. Black elderberry (Sambucus nigra) has been used to treat cold and flu symptoms, but there are no large-scale studies or meta-analyses. This meta-analysis quantifies the effects of elderberry supplementation and evaluates moderators including vaccination status and the underlying pathology. This analysis included a total of 180 participants and evaluates
Physiological effects of the AntiBac ingredients: bile acids, elderberry, turmeric, white horehound, king of bitter, garlic
An expert discussion on the composition of AntiBac capsules and their physiological effects, which include: black elderberry supports the immune system to protect the human body. Garlic helps to maintain the microbiological balance of the gut and to defend against harmful bacteria and microorganisms. Bitter andrographis helps the body's natural defences, particularly at the level of the upper respiratory tract. Medicinal orchid helps the intestinal tract, contributing to healthy digestion and the normal functioning of the liver and bile. Turmeric + Black Pepper supports the immune system, lung and respiratory tract health and protection against allergies, it is a powerful antioxidant. More information in the video! Source: D1 Tv -...
B16 - Preventing the Common Cold With a Garlic Supplement
One hundred forty-six volunteers were randomised to receive a placebo or an allicin-containing garlic supplement, one capsule daily, over a 12-week period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. The active-treatment group had significantly fewer colds than the placebo group (24 vs 65, P<.001). The placebo group, in contrast, recorded significantly more days challenged virally (366 vs 111, P<.005) and a significantly longer duration of symptoms (5.01 vs 1.52 days, P<.001). Consequently, volunteers in the active group were less likely to get...
B21, C10 - COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?
COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy? Download - PDF Introduction The outbreak of coronavirus SARS-Cov-2 disease (COVID-19) in Wuhan (China) in late 2019 and its worldwide spread has caused hundreds of thousands of deaths so far. As of July 2020, the disease seems to be mostly affecting Europe and the Americas. Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. Older people and those with underlying medical problems such as cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to recover.
C12 - A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection
A randomized, double blind placebo controlled clinical study was conducted to evaluate the efficacy of KalmCold™, an extract of Andrographis paniculata, in patients with uncomplicated upper respiratory tract infection (URTI). The assessment involved quantification of symptom scores by Visual Analogue Scale. Nine self-evaluated symptoms of cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance were scored. A total of 223 patients of both sexes were randomized in two groups which received either KalmCold™ (200 mg/day) or placebo in a double blind manner. In both the treatments, mean scores of all symptoms showed a decreasing trend...
C13 - A randomized, controlled study of Kan Jang versus amantadine in the treatment of influenza in Volgograd
Two randomized, parallel-group clinical studies with a verum and a control group were performed to investigate the effect of a standardized extract (SHA-10) of Andrographis panaiculata (N.) fixed combination Kan Jang in the treatment of diagnosed influenza viral infection. The pilot study was performed on 540 patients with 71 Kan Jang-treated patients with the second phase conducted enrolling 66 patients. The differences in the duration of sick leave and frequency of post-influenza complications indicate that the Kan Jang phytopreparation not only contributes to faster recovery, but also reduces the risk of post-influenza complications. Kan Jang was well tolerated by patients....
C17 - Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children
Andrographis paniculata (Chuān Xīn LiaÂn) for symptomatic relief of acute respiratory tract infections in adults and children: a systematic review and meta-analysis Download - PDF Abstract Introduction: Antimicrobial resistance (AMR) is a substantial threat to public health. Safe and effective alternatives are required to reduce unnecessary antibiotic prescribing. Andrographis Paniculata (A. Paniculata, Chuān Xīn LiaÂn) has traditionally been used in Indian and Chinese herbal medicine for cough, cold and influenza, suggesting a role in respiratory tract infections (RTIs). This systematic review aimed to evaluate the clinical effectiveness and safety of A. Paniculata for symptoms of acute RTIs (ARTIs). Results: Thirty-three
D1 - An Insight into a Blockbuster Phytomedicine; Marrubium vulgare L. Herb. More of a Myth than a Reality?
Aerial parts and the root of Marrubium vulgare L. (white horehound) have been traditionally used in Europe and in southern and eastern Mediterranean countries. During colonization, the plant was introduced in America to great levels of popularity because of the simplicity of its growing; it was especially popular in Mexico and Brazil, where it has been known as 'maromba', 'marroio' or 'marroio-branco'. Ethnopharmacological uses of M. vulgare include treating respiratory diseases such as acute or chronic bronchitis, colds and asthma. The plant is also used in cases where there is a lack of appetite or dyspepsia and for diagnosed type...
Direct or indirect effect of bile acids: Play a role in relieving migraine headaches
Direct or indirect effect of bile acids: Contributes to the relief of psoriasis
Direct or indirect effect of bile acids: May contribute to increase cell longevity, thus preserving youthfulness
Direct or indirect effect of bile acids: Play a role in alleviating the negative effects of stress on digestion
Direct or indirect effect of bile acids: Involved in relieving dry skin and joint pain, helps to relieve acne skin problems
Direct or indirect effect of bile acids: Contributes to the relief of hay fever symptoms
C12 - A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection
A randomized, double blind placebo controlled clinical study was conducted to evaluate the efficacy of KalmCold™, an extract of Andrographis paniculata, in patients with uncomplicated upper respiratory tract infection (URTI). The assessment involved quantification of symptom scores by Visual Analogue Scale. Nine self-evaluated symptoms of cough, expectoration, nasal discharge, headache, fever, sore throat, earache, malaise/fatigue and sleep disturbance were scored. A total of 223 patients of both sexes were randomized in two groups which received either KalmCold™ (200 mg/day) or placebo in a double blind manner. In both the treatments, mean scores of all symptoms showed a decreasing trend...
Hungarian and international publications and uses of active substances
The official Hungarian and international literature provides a wide range of theoretical background, scientific studies and practical experience on the active ingredients in the product. It is mandatory for the informed consumer to provide information about what he is buying. These information aims to provide consumers with adequate and complete information and to help them make informed and informed choices by outlining the literature on the physiological effects of bile acids and herbal remedies. This information has been prepared in full compliance with the general provisions of Directive 2011/83/EU of the European Parliament and of the Council on consumer protection, the provisions of Directive 2002/46/EC of the European Parliament and of the Council on the labelling of foodstuffs and Directive 2005/29/EC of the European Parliament and of the Council prohibiting unfair business-to-consumer commercial practices, bearing in mind the aim of the legislation to provide consumers with the fullest and most detailed information possible about the product they are buying and its ingredients. The information on the ingredients of the product is for information purposes and does not refer to the overall effects of the product, which are specifically mentioned in the product information.
Everyone uses GALLMET at their own risk and it is recommended that you check with your doctor!
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