In people with biliary disease, pancreatic dysfunction is more common. In such cases, pancreatic function, which involves the production of exocrine digestive fluid, may be impaired first. In this case, if the pancreas is starved of pancreatic enzyme, it can cause a self-digestive process and inflammation, which, if it occurs repeatedly, can also inhibit the function of the parts responsible for insulin production, causing not only indigestion but also diabetes. This is why bile acid supplementation is recommended for people with biliary disease to prevent this from happening.

A short interview with Dr. Erika Balaicza (doctor, internist, naturopath)
Source: Fix TV - Sinus programme 2015.06.08.