Cartilage protection & long-term support
Take care of your joints for comfort and everyday movement with scientifically researched ingredients!
Do not just mask the symptoms! Support your joints with ingredients that research shows can help maintain normal cartilage structure and joint function!
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Our Advice Line: 06-79-326-581 (Hungarian only)
Why do traditional cartilage builders fail to work in the long term?
For long-term cartilage protection, many customers rely on classic glucosamine and chondroitin, yet a comprehensive medical study involving thousands of people found that even when combined, these substances did not clinically significantly reduce joint pain and had no effect on slowing down cartilage wear (joint space narrowing) compared to a placebo.8 For long-term joint support, ingredients that can help normal cartilage function and joint comfort from multiple angles may be beneficial.
GALLMET Joint + Cartilage:
- Inhibits cartilage breakdown: It inhibits the enzymes (MMPs) that "eat up" healthy cartilage tissue with age.
- Supports cartilage preservation: Laboratory tests confirm that Ovomet® reduces the CTX‑II biomarker of cartilage degradation in the body.
- Stable rebuilding: The added copper and Vitamin‑C support the proper formation and stabilisation of new collagen fibres.
Targeted support for processes related to cartilage integrity:
Inhibition of cartilage-degrading enzymes (Ovomet®): Matrix metalloproteinase (MMP) enzymes produced during ageing and inflammation "eat up" the collagen network that builds up cartilage. According to studies, Ovomet® significantly inhibits the unfavourable activity of these MMP enzymes.7, 14 In a study, biochemical tests confirm that taking eggshell membrane reduces the signs of cartilage degradation in the urine (such as CTX‑II).4, 9
Structural rebuilding (copper and Vitamin‑C): Vitamin‑C contributes to normal collagen formation. Copper is a cofactor of the lysyl oxidase enzyme, which takes part in the formation of covalent cross-links between collagen fibres, thereby potentially contributing to the mechanical stability of cartilage and other connective tissues.
Frequently Asked Questions
- How does the eggshell membrane support articular cartilage integrity?
Based on research conducted with eggshell membrane, the ingredient may support joint comfort, ease of movement, and daily load capacity. In studies, it has shown favourable results in reducing pain and stiffness, while potentially influencing several biological processes associated with cartilage breakdown.9, 14 - What are matrix metalloproteinase (MMP) enzymes and why are they harmful?
MMPs are biological enzymes that are overproduced in the body with age or in the event of an injury, and begin to break down healthy cartilage tissue. Favourably influencing the activity of MMPs can be important in mitigating the processes associated with cartilage breakdown.
- Wandel S. et al., “Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis”, BMJ, 2010. https://www.bmj.com/content/341/bmj.c4675
- Ganpeng Yu et al., “Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis”, BMC, 2020. https://pmc.ncbi.nlm.nih.gov/articles/PMC7368679/
- Aguirre A. et al., “Beneficial Effects of Oral Supplementation With Ovoderm on Human Joint Connective Tissue”, J Diet Suppl., 2021. https://pmc.ncbi.nlm.nih.gov/articles/PMC9182852/
- Ruff K.J. et al., “Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee”, Clin Interv Aging, 2009. https://pmc.ncbi.nlm.nih.gov/articles/PMC2711914/
- Menghini L. et al., “Devil’s claw (Harpagophytum procumbens) and chronic inflammatory diseases”, J Ethnopharmacol., 2019. https://pmc.ncbi.nlm.nih.gov/articles/PMC8548091/
- Zhu X. et al., “Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis”, J Orthop Surg Res., 2018. https://pmc.ncbi.nlm.nih.gov/articles/PMC6035477/
- Gil-Quintana E. et al., “Eggshell Membrane: A Possible New Natural Therapeutic for Joint and Connective Tissue Disorders”, Int J Mol Sci., 2024. https://pmc.ncbi.nlm.nih.gov/articles/PMC11206400/
- Reichenbach S. et al., “Meta-analysis: chondroitin for osteoarthritis of the knee or hip”, Ann Intern Med., 2007. https://pubmed.ncbi.nlm.nih.gov/20847017/
- OVOMET® Health Efficacy Study – Pilot Study Standard, NaturalProtein. https://www.naturalprotein.cz/upload/images/other/wnda-ovomet-health-efficacy-pilot-study-standard-january15-v0.pdf
- Ovomet® – Clinical Research Data Summary – Silver Fern™ Brand. https://www.silverfernbrand.com/pages/ovomet-clinical-research-data-summary
- Efficacy of Eggshell Membrane in Knee Osteoarthritis: A Systematic Review and Meta-Analysis. https://pmc.ncbi.nlm.nih.gov/articles/PMC11356944/
- Glucosamine and chondroitin dosage recommendations – consensus academic search engine. https://consensus.app/questions/glucosamine-and-chondroitin-dosage-recommendations/
- The Truth About Glucosamine and Chondroitin Sulphate | Orthopaedic Associates of Port Huron. https://www.oaph.com/about/patient-education/patient-education-articles/truth-about-glucosamine-chondroitin-sulfate
- Eggshell Membrane: The Natural Health Powerhouse | Eggnovo. https://eggnovo.com/eggshell-a-high-potential-natural-ingredient-for-health-and-wellness/
- Safety of egg membrane hydrolysate as a novel food pursuant to Regulation (EU) 2015/2283. https://pmc.ncbi.nlm.nih.gov/articles/PMC7009436/
- The use of glucosamine and chondroitin to treat osteoarthritis: a review of the literature. https://pmc.ncbi.nlm.nih.gov/articles/PMC6565901/
- Eggshell membrane: A possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies. https://pmc.ncbi.nlm.nih.gov/articles/PMC2697588/
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