Title: Dr. Péter Légrády - Bile acid and cholesterol

Place of appearance: Weekly Pharmacy 17 March 1992.

There is a chemical structural relationship between cholesterol and bile acid, so as a by-product, it was found that cholesterol is reduced by 20-25%. The same can be achieved with very expensive drugs. The drug, as I said, is expensive, and we achieved the same thing by adjusting the metabolism of bile acid - and without side effects.
- It is not enough to look at cholesterol, you also need to look at what it breaks down into. What is the point of cholesterol? A certain amount is taken up by the body - however much cholesterol we eat. If you don't eat enough cholesterol, there is no barrier to internal formation. There are extreme cases, some people have it so high. There are drugs to break it down. If you take bile acid out of the body by taking a drug, you increase cholesterol breakdown. But bile acid is very phytotoxic to the body, and if I take it out, there are huge side effects. In addition, if I bind the bile acid in the intestine, the cholesterol from outside will not be absorbed, it will not have an inhibitory effect, and even if the drug binds the bile acid, it will not be effective in lowering cholesterol.